生命科学仪器2024，Vol.22Issue(2)：14-16,3.DOI:10.11967/2024220405
难治与非难治特发性全面性癫痫患者磁共振脑灰质体积差异研究
MagneticResonance Brain Gray Matter Volume Differences in Patients with Refractory And Non-refractory Idiopathic Generalized Epilepsy
杨建新 1刘军强 1黎义 1何嘉昱1
作者信息
- 1. 上海市第一人民医院酒泉医院(酒泉市人民医院),甘肃酒泉 735000
- 折叠
摘要
Abstract
Objective:To explore and analyze the difference of gray matter volume in patients with refractory and re-fractory idiopathic generalized epilepsy examined by magnetic resonance imaging.Methods:A total of 105 epileptic patients admitted to our hospital from January 2021 to December 2023 were selected,all of whom received routine sequence examination and high-resolution 3D-T1WI structural images,and the differences of gray matter volume displayed by the two examination methods were compared.Results:In the left superior temporal gyrus and the right inferior frontal gyrus,patients with intractable epilepsy showed smaller gray matter volume.In bilateral cerebellar lobes,the volume of gray matter is relatively large.There was significant difference in gray matter volume between patients with intractable epilepsy and those without intractable epilepsy(P＜0.05).Conclusion:There are some differences in brain structure between patients with refractory and non-refractory idiopathic generalized epilepsy,and the brain gray matter damage is significant,which may be the key pathological feature of refractory idiopathic generalized epilepsy and should be paid attention to and further studied.关键词
难治性/特发性/全面性/癫痫/脑灰质体积Key words
Infracrefractory/Idiopathic/Comprehensive/Epilepsy/Gray matter volume分类
医药卫生引用本文复制引用
杨建新,刘军强,黎义,何嘉昱..难治与非难治特发性全面性癫痫患者磁共振脑灰质体积差异研究[J].生命科学仪器,2024,22(2):14-16,3.
