上海针灸杂志2024，Vol.43Issue(6)：621-626,6.DOI:10.13460/j.issn.1005-0957.2024.06.0621
电针辅助药物治疗社交恐惧症的疗效观察及对预后的影响
Observation of the therapeutic effect of electroacupuncture combined with medication on social phobia and its influence on prognosis
摘要
Abstract
Objective To observe the clinical efficacy of electroacupuncture combined with Paroxetine and Sulpiride in the treatment of social phobia and its influence on neuroelectrophysiology and prognosis.Method Ninety patients with social phobia were randomly divided into a trial group and a control group,with 45 cases in each group.Both groups were given psychological counseling.The control group was treated with Paroxetine and Sulpiride,and the trial group was treated with electroacupuncture in addition to the medication of the control group.The clinical efficacy and adverse reactions were compared between the two groups.The electrophysiological indexes(MMN amplitude,MMN latency and N2 target latency),autonomic nerve function indexes[standard deviation of the mean RR interval(SDANN),the percentage of the number of neighbouring normal sinus RR intervals with a 50-ms difference(PNN50)and root mean square of the differences between successive RR intervals(RMSSD)],Liebowitz social anxiety scale(LSAS)score,self-rating anxiety scale(SAS)score and generic quality of life inventory-74(GQOLI-74)score were observed before and after treatment in the two groups.Result The total effective rate of the trial group was higher than that of the control group,the difference between the two groups was statistically significant(P＜0.05).After 1 month of treatment and after treatment,the MMN latency,N2 target latency,LSAS score and SAS score of the trial group were lower than those of the control group,and the MMN amplitude and SDANN,RMSSD and PNN50 were higher than those of the control group(P＜0.05);after treatment,the scores of somatic functioning,psychological functioning,social functioning and material life of the trial group were higher than those of the control group(P＜0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P＜0.05).Conclusion The efficacy of electroacupuncture combined with Paroxetine and Sulpiride in the treatment of social phobia is better than that of drug monotherapy,which can improve clinical symptoms,regulate neuroelectrophysiology and autonomic nerve function,and improve prognosis.关键词
针刺疗法/电针/针药并用/恐惧症,社交/焦虑/预后/神经电生理Key words
Acupuncture therapy/Electroacupuncture/Acupuncture medication combined/Phobia,Social/Anxiety/Prognosis/Neuroelectrophysiology分类
中医学引用本文复制引用
张新宇,杨柳,武长继..电针辅助药物治疗社交恐惧症的疗效观察及对预后的影响[J].上海针灸杂志,2024,43(6):621-626,6.基金项目
张家口市科学技术研究与发展计划项目(1821101D) （1821101D）
