天然产物研究与开发2024，Vol.36Issue(6)：982-985,962,5.DOI:10.16333/j.1001-6880.2024.6.008
怀山药内生真菌Chaetomium sp.的次生代谢产物研究
Secondary metabolites from the endophytic Chaetomium sp.of Dioscorea opposita
摘要
Abstract
In this study,the secondary metabolites of an endophytic Chaetomium sp.L-45 from Dioscorea opposita were isola-ted and identified.The ethyl acetate extract of the rice fermentation of the fungus were separated by silica gel column chroma-tography,Sephadex LH-20,semi-preparative High-performance liquid chromatography,etc.,and the chemical structures of the compounds were identified by NMR and HR-ESI-MS analysis.As a result,four compounds were isolated and identified as 3,4-dimethoxy-5-hydroxy-6-propyl-benzoic acid(1),5-isoprenylindole-3-carboxylic acid(2),lecanorin(3),and ergosterol(4).Among them,compound 1 is a new compound,compounds 2 and 3 were isolated from genus Chaetomium for the first time.关键词
毛壳菌/次生代谢产物/提取分离/结构鉴定Key words
Chaetomium sp./secondary metabolites/extraction and isolation/structure elucidation分类
医药卫生引用本文复制引用
盛蒙珂,赵莹菲,田若丹,文春南,刘淼,麻兵继..怀山药内生真菌Chaetomium sp.的次生代谢产物研究[J].天然产物研究与开发,2024,36(6):982-985,962,5.基金项目
国家自然科学基金(U1604169) （U1604169）
河南省自然科学基金(232300421127) （232300421127）
河南农业大学博士启动基金(30500662) （30500662）
