汕头大学医学院学报2024，Vol.37Issue(2)：71-75,5.DOI:10.13401/j.cnki.jsumc.2024.02.003
配戴角膜塑形镜对青少年近视患者眼表的影响
The effect of wearing orthokeratology on the ocular surface in adolescent myopia patients
李浩 1李丹 1娄智因 1陈泽雄 1林世斌1
作者信息
- 1. 汕头大学·香港中文大学联合汕头国际眼科中心,广东 汕头 515041
- 折叠
摘要
Abstract
Objective:To investigate the effects of orthokeratology on the ocular surface in adolescent myopia patients and the differences in the effects of different design types of orthokeratology on the ocular surface.Methods:Prospective cohort study.Forty-one adolescent myopia patients who attended Joint Shantou International Eye Center and chose to wear orthokeratology lenses from June 2021 to March 2022 were selected,and their right eyes were chosen as the subject eyes.The patients were divided into VST group(21 eyes)and CRT group(20 eyes)according to the type of orthokeratology they tried on.There were 8 males and 13 females in the VST group with the age of(10.7±1.7)years,and 8 males and 12 females in the CRT group with the age of(10.4±1.8)years.Ocular surface disease index(OSDI)scores,tear meniscus height(TMH),noninvasive tear break-up time(NIBUT),basal tear secretion,ocular redness index(ORI),and corneal epithelial fluorescein staining of the study subjects were examined at follow-up before and 1 and 3 months after lens wear,respectively.Results:In adolescent myopia patients,OSDI and ORI were increased and NIBUT was decreased at 1 and 3 months after orthokeratology lenses fitting compared with before lenses(both P<0.05),and there was no difference in the TMH and the basal tear secretion(both P>0.05).The increase in corneal epithelial pitting after lens wear was mainly dominated by grade Ⅰ and Ⅱ pitting,and there was no difference between 1 month and 3 months after lens wear(Z=-0.124,P>0.05).There were no statistically significant differences in OSDI,TMH,NIBUT,basal tear secretion,ORI,and corneal epithelial fluorescein staining between the two groups before and after lens wear(all P>0.05).Conclusion:Short-term wear of orthokeratology does not affect tear production in adolescent myopia patients,but causes mild discomfort,as well as decreasing tear film stability and increasing corneal epithelial damage.There is no difference in the effects of VST-and CRT-type orthokeratology on the ocular surface.关键词
角膜塑形镜/青少年/近视/眼表Key words
orthokeratology/adolescent/myopia/ocular surface分类
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李浩,李丹,娄智因,陈泽雄,林世斌..配戴角膜塑形镜对青少年近视患者眼表的影响[J].汕头大学医学院学报,2024,37(2):71-75,5.
