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儿童清咽解热口服液体外抗肠道病毒71型作用

刘燕琼

妇儿健康导刊2024,Vol.3Issue(12):194-198,5.
妇儿健康导刊2024,Vol.3Issue(12):194-198,5.

儿童清咽解热口服液体外抗肠道病毒71型作用

Anti-enterovirus 71 effect of Ertong Qingyan Jiere Koufuye in vitro

刘燕琼1

作者信息

  • 1. 广州市白云区石井人民医院儿科,广东广州 510400
  • 折叠

摘要

Abstract

Objective To study the anti-enterovirus 71 effect of Ertong Qingyan Jiere Koufuye in vitro.Methods With guanidine hydrochloride as positive control,CellTiter-GloTM was used to determine the cytotoxicity of the tested samples at Vero-E6 cell level,and the expression level of enterovirus protein was determined by indirect immunofluorescence assay,so as to evaluate the antiviral effect of Ertong Qingyan Jiere Koufuye on EV71.Results The median cytotoxic concentration for Vero-E6 cells was 127.2 mg/ml,the median effective concentration for EV71 virus replication inhibition was 3.193 mg/ml,and the selection index was 39.8.Conclusion On the level of Vero-E6 cells,Ertong Qingyan Jiere Koufuye has obvious antiviral effect on EV71.

关键词

儿童清咽解热口服液/肠道病毒71型/抗病毒作用

Key words

Ertong Qingyan Jiere Koufuye/Enterovirus 71/Antiviral effect

分类

医药卫生

引用本文复制引用

刘燕琼..儿童清咽解热口服液体外抗肠道病毒71型作用[J].妇儿健康导刊,2024,3(12):194-198,5.

妇儿健康导刊

2097-115X

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