世界中医药2024，Vol.19Issue(8)：1092-1098,1107,8.DOI:10.3969/j.issn.1673-7202.2024.08.006
9个常用经典名方治疗成人支气管哮喘疗效的网状Meta分析
A Network Meta-analysis of the Efficacy of Nine Commonly Used Classical Prescriptions in Treating Bronchial Asthma in Adults
摘要
Abstract
Objective:To evaluate the efficacy of nine classical prescriptions in treating bronchial asthma in adults with different syndromes by a network meta-analysis and provide a therapeutic basis for the clinical treatment of bronchial asthma.Methods:The randomized controlled trials(RCTs)of nine classical prescriptions(Yupingfeng Powder,Sangbaipi Decoction,Maxing Shigan De-coction,Suzi Jiangqi Decoction,Sanzi Yangqin Decoction,Xiaoqinglong Decoction,Dingchuan Decoction,Jinshui Liujun Decoction,and Shegan Mahuang Decoction)for treating bronchial asthma in adults were searched against the China National Knowledge Infra-structure(CNKI),China Science Periodical Database(CSPD),and Chinese Citation Database(CCD)with the time interval from inception to December 20,2021.The network meta-analysis was conducted for the included articles in Stata 16.0.Results:A total of 41 articles were included in this study.The five best treatment regimens in improving the clinical response rate were Shegan Mahuang Decoction+Western Medicine＞Yupingfeng Powder+Western Medicine＞Jinshui Liujun Decoction+Western Medicine＞Dingchuan Decoction+Western Medicine＞Maxing Shigan Decoction+Western Medicine.In terms of improving the forced expiratory volume in the 1st second(FEV1％),the best 5 treatment regimens were Yupingfeng Powder+Western Medicine＞Shegan Mahuang Decoction+Western Medicine＞Dingchuan Decoction+Western Medicine＞Xiaoqinglong Decoction+Western Medicine＞Suzi Jiangqi Decoction+Western Medicine.The cases of adverse reactions in the observation group were all fewer than those in the control group.Conclusion:All the nine commonly used classical prescriptions combined with Western medicine could increase the clinical response rate and FEV1％and reduce the cases of adverse reactions compared with Western medicine alone.Due to limitations in the quality of the included articles,more rigorously designed RCTs are needed to verify the conclusion.关键词
经典名方/成人支气管哮喘/临床疗效/肺功能/网状Meta分析/不良反应/随机对照试验Key words
Classical prescriptions/Bronchial asthma in adults/Clinical efficacy/Pulmonary function/Network meta-analysis/Adverse reactions/Randomized controlled trial分类
医药卫生引用本文复制引用
张志杰,黄贵锐,张诗瑜,黄帅阳,崔红生..9个常用经典名方治疗成人支气管哮喘疗效的网状Meta分析[J].世界中医药,2024,19(8):1092-1098,1107,8.基金项目
国家自然科学基金面上项目(82074390) （82074390）
