云南化工2024，Vol.51Issue(6)：39-44,6.DOI:10.3969/j.issn.1004-275X.2024.06.10
口罩伴侣清凉提神水凝胶贴片的制备工艺研究
Study on Preparation of Mask Mate Cool Refreshing Hydrogel Patch
摘要
Abstract
(Objective)To prepare an oil of peppermint gel patch,which is attached to the inner wall of a mask,to optimize the mask wearing for prolonged wear,such as boredom,mental fatigue,stench.(Methods)The raw materials are polyvinyl alcohol(PVA)and chitosan(CS).The oil of peppermint/PVA/CS composite hydrogel patch is prepared by cyclic freezing/thawing method.The optimum preparation process is optimized by RSM,and the optimum drug loading of the oil of peppermint is determined by single blind method.(Results)The optimal preparation conditions are as follows:PVA/CS ratio 5.3:1,freezing time 12.5 h,freezing times 4 times,oil of peppermint 0.5％～0.6％.(Conclusion)The hydrogel patch prepared by RSM has the advantages of good viscosity,easy to use,small size,long lasting fragrance,safe,non-toxic,non-irritant and so on.It is reasonable and feasible to optimize the preparation process of oil of peppermint.关键词
水凝胶贴片/单因素试验/响应面优化/单盲法Key words
Hydrogel patch/One-factor test/Response surface optimization/Single-blind methodology分类
医药卫生引用本文复制引用
李若涵,汪千千,张艳焱,徐剑..口罩伴侣清凉提神水凝胶贴片的制备工艺研究[J].云南化工,2024,51(6):39-44,6.基金项目
贵州中医药大学大学生创新创业训练计划项目(贵中医大创合字(2022)107号). （贵中医大创合字(2022）
