中风与神经疾病杂志2024，Vol.41Issue(6)：550-554,5.DOI:10.19845/j.cnki.zfysjjbzz.2024.0105
快速和缓慢进展型脑干梗死的影响因素
Influencing factors for rapidly or slowly progressive brainstem infarction
摘要
Abstract
Objective To investigate the influencing factors for slowly progressive brainstem infarction and rapidly progressive brainstem infarction in patients with severe stenosis or occlusion of basilar artery.Methods A retrospective analysis was performed for 501 patients who attended Zhengzhou University People's Hospital from January 2013 to Decem-ber 2022 and were diagnosed with first-episode brainstem infarction after severe stenosis or occlusion of basilar artery by HR-MRI.The core volume of brainstem infarction was manually calculated,and the distribution of brainstem infarct vol-ume was analyzed.According to brainstem infarct volume and the time from stroke attack to imaging,the patients were di-vided into slowly progressive brainstem infarction group(0-<1 ml,6-24 hours)and rapidly progressive brainstem infarc-tion group(>5 ml,0-<6 hours),and the two groups were compared in terms of risk factors and collateral circula-tion.Results The 501 patients with severe stenosis or occlusion of basilar artery had a mean age of 66.14±10.37 years,among whom 39.13%were male patients.According to predefined thresholds,29 patients(16.29%)with severe stenosis or occlusion of basilar artery in the time window of 0-<6 hours were diagnosed with rapidly progressive brainstem infarc-tion,and 56 patients(17.34%)in the time window of 6-24 hours were diagnosed with slowly progressive brainstem infarc-tion.There were no significant differences between the two groups in the risk factors such as age,sex,NIHSS score,hy-pertension,diabetes,hyperlipidemia,and history of atrial fibrillation,coronary artery disease,and smoking.The Pear-son correlation analysis showed that collateral circulation in patients with severe stenosis or occlusion of the basilar artery was negatively correlated with rapidly progressive brainstem infarction(r=-0.619,P<0.001).Conclusions After se-vere stenosis or occlusion of the basilar artery,patients with good collateral circulation often have slowly progressive brain-stem infarction,while patients with poor collateral circulation often have rapidly progressive brainstem infarction.关键词
基底动脉闭塞/缓慢进展/快速进展/脑干梗死Key words
Basilar artery occlusion/Slow progression/Rapid progression/Brainstem infarction分类
医药卫生引用本文复制引用
师晶晶,蔡萌萌,晁琳琳,赵建华..快速和缓慢进展型脑干梗死的影响因素[J].中风与神经疾病杂志,2024,41(6):550-554,5.基金项目
河南省医学科技攻关计划项目(SBGJ202102034) （SBGJ202102034）
河南省科技计划重点项目(22210231077) （22210231077）
