COX1基因多态性与血小板聚集功能在缺血性脑卒中复发患者中的交互作用OACSTPCD
Interaction between COX1 gene polymorphism and platelet aggregation function in patients with recurrent isch-emic stroke
目的 探讨COX1基因多态性与血小板聚集功能的交互作用对缺血性脑卒中复发患者的影响.方法 选择2020年7月—2023年7月缺血性脑卒中复发患者70例为观察组,另选择同期体检的70例健康者为对照组.比较两组的一般资料并分析COX1基因多态性.检测并比较两组患者COX1基因多态性位点基因型及等位基因频率分布.比较观察组不同基因型血小板聚集率水平及与缺血性脑卒中复发易感性的关系及交互作用.结果 两组的血小板计数、COX1、血小板聚集率差异具有统计学意…查看全部>>
Objective To investigate the influence of the interaction between COX1 gene polymorphism and plate-let aggregation function on patients with recurrent ischemic stroke.Methods A total of 70 patients with recurrent isch-emic stroke from July 2020 to July 2023 were enrolled as observation group,and 70 healthy individuals who underwent physical examination during the same period of time were enrolled as control group.General data were compared between the two gr…查看全部>>
刘星亮;范磊;娄展;宋征宇
河北北方学院附属第一医院神经内科,河北 张家口 075000河北北方学院附属第一医院神经内科,河北 张家口 075000河北北方学院附属第一医院神经内科,河北 张家口 075000河北北方学院附属第一医院神经内科,河北 张家口 075000
临床医学
COX1基因多态性血小板聚集缺血性脑卒中复发
COX1Genetic polymorphismPlatelet aggregationRecurrence of ischemic stroke
《中风与神经疾病杂志》 2024 (6)
555-559,5
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