云南化工2024，Vol.51Issue(6)：1-3,3.DOI:10.3969/j.issn.1004-275X.2024.06.01
微球制剂的研究进展
Progress in Microsphere Preparations
摘要
Abstract
In recent years,drug-loaded microsphere preparation prepared by biodegradable polymer materials can be slowly controlled release,which is a research hotspot of high-end new pharmaceutical preparations.The key factor in the preparation of microsphere preparations lies in the selection of suitable polymer materials and production technology.However,the preparation process of microspheres is complicated and the quality control is difficult,which is only applied in a few products.Now more and more oral biological drugs are difficult to absorb,and slow-release microspheres are much attention in improving patient compliance.This review analyzes the classic microsphere preparation technology and some new techniques of microsphere preparation,and summarizes the morphology,size,particle distribution,drug loading,sealing rate and release degree of microsphere preparations,in order to provide some reference value for the research of microsphere preparations.关键词
生物可降解/微球制剂/缓释/质量评价/研究进展Key words
Biodegradable/Microsphere preparation/Sustained release/Quality evaluation/Research progress分类
药学引用本文复制引用
王晨曦,刘心怡,王婧,王群,朱双双..微球制剂的研究进展[J].云南化工,2024,51(6):1-3,3.基金项目
国家级大学生创新创业训练计划项目,编号:202310380012. （）
