中风与神经疾病杂志2024，Vol.41Issue(6)：499-506,8.DOI:10.19845/j.cnki.zfysjjbzz.2024.0095
膳食炎症指数与罹患癫痫风险的关系研究
Association between dietary inflammatory index and the risk of epilepsy:a cross-sectional analysis based on the National Health and Nutrition Examination Survey data
张玲 1陈邓 2刘凌2
作者信息
- 1. 四川大学华西医院神经内科,四川 成都 610041||成都市第八人民医院,成都医学院附属老年医院,四川 成都 610083
- 2. 四川大学华西医院神经内科,四川 成都 610041
- 折叠
摘要
Abstract
Objective To investigate the association between dietary inflammation and the risk of epilepsy(EP)based on dietary inflammatory index(DII),and to provide a scientific basis for the prevention and treatment of EP in terms of dietary intervention.Methods Related data of the adults aged≥20 years were obtained from the National Health and Nutrition Ex-amination Survey(NHANES)from January 2013 to March 2020.A multivariate logistic regression model was used to investi-gate the association between DII and the risk of EP,and a restricted cubic spline(RCS)regression analysis was used to per-form the linearity test and explore the quantitative relationship between DII score and the risk of EP.The subgroup and interac-tion analyses were used to evaluate the stability of the association between DII and EP across different subgroups.Results A total of 15565 respondents were included in this study,among whom 131 were diagnosed with EP.In the fully adjusted multi-variate logistic regression model,DII,as a continuous variable,was positively associated with the risk of EP[odds ratio(OR)=1.12,95%confidence interval(CI)1.02-1.24,P=0.021].After the tertile categorization of DII,the fully adjusted model showed that the high pro-inflammatory group had a significantly higher risk of EP than the low pro-inflammatory group(OR=1.63,95%CI 1.02-2.6,P=0.039).In the RCS linearity test,DII was positively associated with the risk of EP(non-linearity:P=0.342).The stratified analysis showed that the relationship between DII and the risk of EP remained stable,with no significant interactions observed between subgroups.Conclusion There is a positive correlation between DII and the risk of EP among American adults,and for every unit increase in DII,the risk of EP is increased by 12%.关键词
癫痫/膳食炎症指数/促炎饮食/抗炎饮食Key words
Epilepsy/Dietary inflammatory index/Pro-inflammatory diet/Anti-inflammatory diet分类
医药卫生引用本文复制引用
张玲,陈邓,刘凌..膳食炎症指数与罹患癫痫风险的关系研究[J].中风与神经疾病杂志,2024,41(6):499-506,8.
