涎腺二维超声及其弹性成像在干燥综合征中的评估价值OA北大核心CSTPCD

Objective:To assess the differences in two-dimensional ultrasonography and shear wave elastography(2D-SWE)of the parotid,submandibular and sublingual glands between the control and Sjogren's syndrome(SS)group,and to evaluate the clinical diagnostic efficiency of conventional ultrasonography and elastography in SS.Methods:This study enrolled 100 non-SS patients(control group)and 90 SS patients(SS group).The two-dimensional scores of ultrasonography and the elastic modulus of 2D-SWE in the parotid,submandibular and sublingual glands were analyzed.The receiver operating characteristic(ROC)curve was used to evaluate the diagnostic performance of the two-dimensional score and the speed of SWE in SS.Results:There were statistically significant differences in the two-dimensional scores and the elastic modulus of SWE of the three glands between the control group and the SS group(P<0.01).The area under the curve(AUC)value of parotid gland was higher than that of submandibular gland(P<0.01),and the AUC value of submandibular gland was higher than that of sublingual gland(P<0.01).Based on the Youden index,the sensitivity and specificity of parotid,submandibular and sublingual glands for diagnosing SS at the optimal cut-off value were 83.3%,93.0%,and 90.0%,51.0%,66.7%,and 56.0%,respectively.The AUC values of elastic modulus of SWE in parotid gland,submandibular gland and sublingual gland for diagnosing SS were higher than those of the two-dimensional score.Conclusions:Two-dimensional ultrasound of parotid gland,submandibular gland and sublingual gland has certain clinical diagnostic efficacy in the diagnosis of SS,and the diagnostic performance of elastic modulus of SWE in salivary gland is superior to that of two-dimensional score in SS.