18F-FDG PET/CT对偶发性进展期结直肠腺瘤的诊断价值OA北大核心CSTPCD

Objective:The relationship between the maximum standardized uptake value(SUVmax)of 18F-FDG PET/CT and the advanced colorectal adenoma remains unclear.The purpose of this study was to investigate the diagnostic performance of SUVmax in differentiating advanced and non-advanced colorectal adenomas.Methods:This study enrolled 153 patients with colorectal adenoma accidentally diagnosed by 18F-FDG PET/CT.According to the risk of carcinogenesis,the patients were di-vided into two groups with advanced and non-advanced colorectal adenoma.Focal SUVmax of PET/CT was measured.The re-ceiver operating characteristic(ROC)curve was used to determine the optimal cut-off values for the two groups.Univariate and multivariate analyses were performed using Logistic regression models to identify independent risk factors.Results:There was statistical significance between SUVmax values of the advanced and non-advanced colorectal adenoma groups(8.61±4.01 vs.5.02±2.00,P<0.05).Logistic multivariate regression analysis showed that SUVmax,CEA,CA125 and occult blood were the in-dependent risk factors.The area under the curve(AUC)of SUVmax was 0.810,and the AUC of the combination of SUVmax,CEA,CA125 and occult blood was 0.879.Conclusions:The SUVmax value based on 18F-FDG PET/CT imaging is an inde-pendent risk factor for predicting advanced colorectal adenoma,which can be used as a non-invasive quantitative diagnostic tool to guide preoperative treatment strategies.