心脏双源CT与心脏磁共振成像计算细胞外容积用于评价慢性心力衰竭患者心肌弥漫性纤维化的对比研究OACSTPCD
A comparative study of cardiac dual-source CT-ECV and MRI-ECV in evaluating diffuse myocardial fibrosis in patients with chronic heart failure
目的:探究心脏双源CT(DSCT)与心脏磁共振成像(MRI)计算细胞外容积(ECV),评价慢性心力衰竭(CHF)患者心肌纤维化(MF)的可行性和准确性.方法:选取2019年1月至2021年6月新疆维吾尔自治区人民医院收治的67例CHF患者,分别行DSCT和MRI扫描,计算ECV,比较两种方法对MF的诊断效能.结果:DSCT-ECV的分配系数(λ)为0.56±0.27,ECV为(33.04±10.68)%;而MRI-ECV的分配系数(λ)为0.51±0.32,ECV为(29.49±11.14)%.DSCT-ECV与MRI-ECV相比差异无统计学意义(P＞0.05),DSCT-ECV与MRI-ECV诊断CHF患者MF均有较高的灵敏度、特异度和准确率(DSCT-ECV:100%、92.86%和98.51%,MRI-ECV:98.11%、100%和98.51%),两种方式的诊断可靠性比较差异均无统计学意义(P＞0.05).结论:ECV是心力衰竭的可量化技术,且预测心肌弥漫性纤维化能力强,DSCT-ECV和MRI-ECV评价CHF患者的MF准确性高,可用于相关疾病分级、进展监测和治疗指导,而DSCT-ECV较MRI-ECV应用更方便.
Objective:To investigate the feasibility and accuracy of extracellular volume(ECV)values that were calculated respectively by dual-source computed tomography(DSCT)and magnetic resonance imaging(MRI)in evaluating myocardial fibrosis(MF)of patients with chronic heart failure(CHF).Methods:A total of sixty-seven CHF patients admitted to People's Hospital of Xinjiang Uygur Autonomous Region from January 2019 to June 2021 were selected,and they respectively underwent DSCT and MRI scans to calculate ECV.The diagnostic efficacies of the two methods for MF were compared.Results:The distribution coefficient(λ)and ECV values of DSCT-ECV were respectively 0.56±0.27 and(33.04±10.68)%,while those of MRI-ECV were respectively 0.51±0.32 and(29.49±11.14)%.There were significant differences in them between DSCT-ECV and MRI-ECV(P>0.05).Both DSCT-ECV and MRI-ECV had higher sensitivity,specificity and accuracy in diagnosing MF of CHF patients(DSCT-ECV:100%,92.86%and 98.51%,MRI-ECV:98.11%,100%and 98.51%).There was no significant difference in diagnostic reliability between the two methods(P>0.05).Conclusion:ECV is a quantifiable technique for heart failure,which has a strong ability in predicting diffuse myocardial fibrosis.The accuracies of both DSCT-ECV and MRI-ECV are higher in evaluating MF of CHF patients,which can be used in relevant disease grading,progress monitoring and treatment guidance.However,DSCT-ECV has a wider application range and it is more convenient than MRI-ECV.
刘烁;李晓娟;张梦琪;王姗姗
新疆维吾尔自治区人民医院放射影像中心 乌鲁木齐 830001
临床医学
计算机体层成像(CT)磁共振成像(MRI)细胞外容积(ECV)心力衰竭心肌纤维化(MF)
Computed tomography(CT)Magnetic resonance imaging(MRI)Extracellular volume(ECV)Heart failureMyocardial fibrosis(MF)
《中国医学装备》 2024 (006)
45-49 / 5
新疆维吾尔自治区科技计划(2019D01C136) Xinjiang Uygur Autonomous Region science and technology program(2019D01C136)
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