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先天性风疹综合征合并间质性肺炎1例报告

陈经纶 梁宇峰 陶建平

中国实用儿科杂志2024,Vol.39Issue(6):477-480,4.
中国实用儿科杂志2024,Vol.39Issue(6):477-480,4.DOI:10.19538/j.ek2024060615

先天性风疹综合征合并间质性肺炎1例报告

A case report on congenital rubella syndrome complicated with interstitial pneumonia

陈经纶 1梁宇峰 1陶建平1

作者信息

  • 1. 国家儿童区域医疗中心(中南)广州医科大学附属妇女儿童医疗中心PICU,广东广州 510000
  • 折叠

摘要

Abstract

Congenital rubella syndrome is a disease that usually starts in infancy and is caused by rubella infection in the mother's uterus.The main manifestations are hearing impairment,congenital heart malformation,cataract/congenital glaucoma and pigmentary retinopathy,and a few may be complicated by interstitial pneumonia.Nowadays CRS is rare,and there has been no report on cases of CRS complicated with interstitial pneumonia.This article reports a case of URS complicated with interstitial pneumonia starting in infancy who were hospitalized in the Guangzhou women and Children's Medical Center from November 29,2020.The main clinical manifestations were interstitial pneumonia,cataract,hearing impairment,congenital heart malformation,etc.Serum rubella virus-IgM was positive,the alveolar lavage fluid was detected by high throughput seguencing and rubella virus was found,and chest CT showed uniform ground glass interstitial changes in both lungs,which confirmed the diagnosis of CRS complicated with interstitial pneumonia.This article aims to study the harm and prognosis of the disease and strengthen the attention of clinicians by analyzing the pathogenesis,clinical manifestations,laboratory indicators,imaging manifestations,treatment and prognosis of CRS complicated with interstitial pneumonia.

关键词

先天性风疹综合征/间质性肺炎/婴儿

Key words

congenital rubella syndrome/interstitial pneumonia/infant

分类

医药卫生

引用本文复制引用

陈经纶,梁宇峰,陶建平..先天性风疹综合征合并间质性肺炎1例报告[J].中国实用儿科杂志,2024,39(6):477-480,4.

基金项目

广东省自然科学基金面上项目(No.2022A1515010556) (No.2022A1515010556)

西藏自治区自然科学基金组团式援藏医学项目[No.XZ2022ZR-ZY44(Z)] (Z)

中国实用儿科杂志

OA北大核心CSTPCD

1005-2224

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