中国实用儿科杂志2024,Vol.39Issue(6):477-480,4.DOI:10.19538/j.ek2024060615
先天性风疹综合征合并间质性肺炎1例报告
A case report on congenital rubella syndrome complicated with interstitial pneumonia
摘要
Abstract
Congenital rubella syndrome is a disease that usually starts in infancy and is caused by rubella infection in the mother's uterus.The main manifestations are hearing impairment,congenital heart malformation,cataract/congenital glaucoma and pigmentary retinopathy,and a few may be complicated by interstitial pneumonia.Nowadays CRS is rare,and there has been no report on cases of CRS complicated with interstitial pneumonia.This article reports a case of URS complicated with interstitial pneumonia starting in infancy who were hospitalized in the Guangzhou women and Children's Medical Center from November 29,2020.The main clinical manifestations were interstitial pneumonia,cataract,hearing impairment,congenital heart malformation,etc.Serum rubella virus-IgM was positive,the alveolar lavage fluid was detected by high throughput seguencing and rubella virus was found,and chest CT showed uniform ground glass interstitial changes in both lungs,which confirmed the diagnosis of CRS complicated with interstitial pneumonia.This article aims to study the harm and prognosis of the disease and strengthen the attention of clinicians by analyzing the pathogenesis,clinical manifestations,laboratory indicators,imaging manifestations,treatment and prognosis of CRS complicated with interstitial pneumonia.关键词
先天性风疹综合征/间质性肺炎/婴儿Key words
congenital rubella syndrome/interstitial pneumonia/infant分类
医药卫生引用本文复制引用
陈经纶,梁宇峰,陶建平..先天性风疹综合征合并间质性肺炎1例报告[J].中国实用儿科杂志,2024,39(6):477-480,4.基金项目
广东省自然科学基金面上项目(No.2022A1515010556) (No.2022A1515010556)
西藏自治区自然科学基金组团式援藏医学项目[No.XZ2022ZR-ZY44(Z)] (Z)