基于功能性近红外光谱技术探索脑卒中后偏瘫患者不同踝关节牵伸训练任务与皮层活动的相关性OACSTPCD

Objective:To investigate the differences in the regions of interest(ROIs)related to different stretching training tasks of the ankle joint,and to identify the correlations between the tasks and the activation of ROIs in post-stroke patients with hemiplegia.Methods:In this study,26 post-stroke patients with hemiplegia were recruited and divided into 2 groups:14 cases of non-dominant hemispheric group and 12 cases of the dominant hemispheric group.Each participant received several clinical functional assessments before the experiment.A multichannel fNIRS sys-tem was used to monitor and record the oxyhemoglobin(oxy-Hb)in each cortical areas of interest during the experi-mental tasks.Results:The active dorsiflexion and plantar flexion training tasks of ankle joint had higher brain acti-vation than passive ankle dorsiflexion and plantar flexion training and resting state(P＜0.05),while passive train-ing tasks had higher brain activation than resting state(P＜0.05).On the whole,ROIs activation on the affected side was higher than that on the non-affected side in the dominant hemisphere.The lateralization index(LI)of the dominant hemisphere group was more likely to be greater than 0.In the non-dominant hemisphere group,there was a positive correlation between the activation of SMC associated with ankle training and 6MWT walking distance(r=0.5531-0.6165,P＜0.05).Conclusion:There are some differences and correlations between different stretching training tasks of ankle joint and cortical activity in post-stroke patients with hemiplegia.