肿瘤防治研究2024，Vol.51Issue(6)：397-401,5.DOI:10.3971/j.issn.1000-8578.2024.24.0065
免疫治疗时代背景下放疗在晚期食管癌中的应用进展
Progress of Research on Radiotherapy for Advanced Esophageal Cancer in the Era of Immunotherapy
摘要
Abstract
Esophageal cancer is predominantly diagnosed at a locally advanced or distant metastasis stage in patients.Once the disease progresses to the advanced stage,its prognosis is poor,and the median overall survival time of patients receiving traditional chemotherapy is less than one year.Treatment with immune checkpoint inhibitors has provided new opportunities to patients with esophageal cancer and changed the previous treatment pattern.Chemotherapy combined with immunotherapy(PD-1 inhibitor)has become the standard first-line treatment for advanced esophageal cancer.However,chemotherapy combined with immunotherapy have been reported a median overall survival time of only 12.4-17.2 months for patients.Such a survival time remains insufficient to meet clinical needs.Combining systemic treatment with local treatment and seeking new comprehensive treatment models are important research directions for improving efficacy.This article reviews the research progress and prospects of radiotherapy in the treatment of advanced esophageal cancer.关键词
晚期食管癌/免疫治疗/放疗Key words
Advanced esophageal cancer/Immunotherapy/Radiotherapy分类
医药卫生引用本文复制引用
王澜..免疫治疗时代背景下放疗在晚期食管癌中的应用进展[J].肿瘤防治研究,2024,51(6):397-401,5.基金项目
Applicable Medical Tracking Project in Hebei Province(No.GZ2024076) 河北省适用医学跟踪项目(GZ2024076) （No.GZ2024076）
