中国免疫学杂志2024，Vol.40Issue(6)：1292-1296,5.DOI:10.3969/j.issn.1000-484X.2024.06.029
TCR DNA疫苗在自身免疫病中的研究进展
Research progress of TCR DNA vaccine in autoimmune diseases
摘要
Abstract
Autoimmune disease(AID)is a disease in which the body loses tolerance to autoantigens and the immune system attacks its own tissues,resulting in organ and tissue damage and certain clinical manifestations.Studies have proved that pathogenic T cells can be selectively inhibited or killed by TCR vaccine in the treatment of AID,thus bringing broad application prospect.This pa-per briefly summarizes the research status of TCR vaccine in AID field,regarding action mechanism,related diseases and safety of TCR vaccine.关键词
TCR/TCR DNA疫苗/自身免疫病Key words
TCR/TCR DNA vaccine/Autoimmune diseases分类
医药卫生引用本文复制引用
张俊宁,王广宇,欧明林,侯显良..TCR DNA疫苗在自身免疫病中的研究进展[J].中国免疫学杂志,2024,40(6):1292-1296,5.基金项目
国家自然科学基金(82101877) （82101877）
中国博士后科学基金(2021M691239,2023M740344) （2021M691239,2023M740344）
广西自然科学基金(2019GXNSFBA245032,2024GXNSFAA010096) （2019GXNSFBA245032,2024GXNSFAA010096）
桂林市科学研究与技术开发计划项目(20190218-5-5,20210218-2) （20190218-5-5,20210218-2）
广西科技计划项目(桂科AD20238021). （桂科AD20238021）
