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晚期非小细胞肺癌免疫治疗:研究进展和展望

王婧怡 钟雨玲 邬麟

肿瘤防治研究2024,Vol.51Issue(6):409-418,10.
肿瘤防治研究2024,Vol.51Issue(6):409-418,10.DOI:10.3971/j.issn.1000-8578.2024.24.0090

晚期非小细胞肺癌免疫治疗:研究进展和展望

Immunotherapy for Advanced Non-small Cell Lung Cancer:Research Progress and Perspectives

王婧怡 1钟雨玲 2邬麟1

作者信息

  • 1. 410013 长沙,湖南省肿瘤医院/中南大学湘雅医学院附属肿瘤医院胸内二科
  • 2. 421001 衡阳,南华大学衡阳医学院,湖南省肿瘤医院研究生协作培养基地
  • 折叠

摘要

Abstract

Immunotherapy has changed the treatment landscape of advanced non-small cell lung cancer(NSCLC),showing great potential in the treatment of untreated and relapsed or refractory(R/R)patients.However,numerous issues that need further exploration remain with the wide application of immunotherapy.They include the exploration of biomarkers for efficacy prediction,the optimization of immunotherapy modalities,immune-related adverse effects,and the management of special populations.This review summarizes the progress of the research on immunotherapy for advanced NSCLC and discusses its challenges and future directions.

关键词

非小细胞肺癌/免疫治疗/免疫检查点抑制剂

Key words

Non-small cell lung cancer/Immunotherapy/Immune checkpoint inhibitors

分类

医药卫生

引用本文复制引用

王婧怡,钟雨玲,邬麟..晚期非小细胞肺癌免疫治疗:研究进展和展望[J].肿瘤防治研究,2024,51(6):409-418,10.

基金项目

湖南省科技创新计划(2023SK4024、2021SK51121) (2023SK4024、2021SK51121)

湖南省肿瘤医院"科研攀登计划"(2X2020005-5) (2X2020005-5)

北京市希思科临床肿瘤学研究基金会(Y-2019Gene-cast-024) The Science and Technology Innovation Program of Hunan Province(No.2023SK4024,No.2021SK51121) (Y-2019Gene-cast-024)

Hunan Cancer Hospital Climb Plan(No.2X2020005-5) (No.2X2020005-5)

Beijing Xisike Clinical Oncology Research Foundation(No.Y-2019Genecast-024) (No.Y-2019Genecast-024)

肿瘤防治研究

OACSTPCD

1000-8578

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