中国康复理论与实践2024，Vol.30Issue(6)：701-708,8.DOI:10.3969/j.issn.1006-9771.2024.06.010
不同病程脑卒中患者上肢体感诱发电位与感觉、运动功能的相关性
Correlation of upper extremity somatosensory evoked potentials with sensory and motor functions in stroke pa-tients in different stages
摘要
Abstract
Objective To investigate the correlation between somatosensory evoked potentials(SEP)of upper limbs,and sensory and motor functions in stroke patients in different stages. Methods From June,2021 to October,2023,177 stroke patients in Shijiazhuang People's Hospital were diveded into acute stage group(within 14 days,n=25),early recovery group(14 days to one month,n=110)and middle to late recovery group(one to six months,n=42)according to the duration of the disease.General information of the patients was recorded;SEP examination was performed,and N20 lantency and amplitude were recorded.Monofilament touch and two-point discrimination sensation of the patient's hands were tested using the monofila-ment and two-point discrimination tools,respectively;and motor function was assessed with Fugl-Meyer Assess-ment-Upper Extremities(FMA-UE).The correlation between SEP,and the sensory and motor scores in each group was analyzed. Results There was no significant difference in the monofilament tactile and two-point discrimination scores among the three groups(P>0.05).SEP was not correlated with sensory and motor functions in the acute stage group(P>0.05);in the early recovery group,N20 latency was negatively correlated with monofilament tactile sensation(r=-0.267,P=0.005)and positively correlated with two-point discrimination sensation(r=0.220,P=0.021),and N20 amplitude was positively correlated with monofilament tactile sensation(r=0.328,P<0.001)and FMA-UE score(r=0.418,P<0.001),and negatively correlated with two-point discrimination(r=-0.405,P<0.001);in the middle to late recovery group,the N20 latency was negatively correlated with FMA-UE score(r=-0.313,P=0.044),and N20 amplitude was positively correlated with monofilament tactile sensation(r=0.598,P<0.001)and FMA-UE score(r=0.393,P=0.010),and negatively correlated with two-point discrimination(r=-0.591,P<0.001).Multiple linear regression analyses showed that the score of monofilament tactile sensa-tion was negatively correlated with N20 latency(β=-0.510,P=0.046),and the FMA-UE score was positively correlated with N20 amplitude(β=0.313,P=0.026)in the middle to late recovery group;in the early recovery group,the two-point discriminative sensation score was negatively correlated with N20 amplitude(β=-0.270,P=0.039). Conclusion The correlation between SEP and sensory and motor functions becomes more significant with the prolonga-tion of disease.关键词
脑卒中/感觉功能/运动功能/体感诱发电位/神经电生理Key words
stroke/sensory function/motor function/somatosensory evoked potentials/neurophysiology分类
医药卫生引用本文复制引用
杨世宁,马将,李红,郭立颖,刘先莹,张莉芳..不同病程脑卒中患者上肢体感诱发电位与感觉、运动功能的相关性[J].中国康复理论与实践,2024,30(6):701-708,8.基金项目
河北省中医药管理局科研计划项目(No.2024130) Supported by Hebei Provincial Administration of Traditional Chinese Medicine Scientific Research Program(No.2024130) （No.2024130）
