吉林大学学报(医学版)2024,Vol.50Issue(3):872-880,9.DOI:10.13481/j.1671-587X.20240335
带状疱疹后遗神经痛疼痛矩阵的研究进展
Research pregress in pain matrix of postherpetic neuralgia
摘要
Abstract
Postherpetic neuralgia(PHN)is a typical chronic neuropathic pain syndrome.Both peripheral and central nervous system mechanisms are believed to be involved in PHN,but the central nervous system-related brain network structure and function are not yet fully elucidated,limiting the study on the clinical analgesic drugs and other intervention strategies.In recent years,the research on pain matrix-related brain networks has helped to reveal the central nervous system regulation mechanism of pain,but there are few reports on the PHN pain matrix.This review summarizes the recent studies on the PHN pain matrix,retrospectively analyzes the functional and structural changes in specific pain-related brain regions,in order to provide the new insights for exploring the effective targeted analgesic treatments.关键词
带状疱疹后遗神经痛/疼痛矩阵/脑区/中枢神经系统/疼痛综合征Key words
Postherpetic neuralgia/Pain matrix/Brain region/Certral nervous system/Pain syndrome分类
医药卫生引用本文复制引用
刘秋平,刘涛,张雪竹..带状疱疹后遗神经痛疼痛矩阵的研究进展[J].吉林大学学报(医学版),2024,50(3):872-880,9.基金项目
天津市科技局重点研发计划科技支撑重点项目(20YFZCSY00810) (20YFZCSY00810)
河北省科技厅省级科技计划项目(20377712D) (20377712D)