吉林医药学院学报2024，Vol.45Issue(4)：241-245,5.
靶向MYC基因抗肿瘤研究进展
Advances in Anti-Tumor Research Targeting MYC Gene
徐冶1
作者信息
- 1. 吉林医药学院,吉林 吉林 132013||肿瘤靶向治疗与转化医学实验室,吉林 吉林 132013
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摘要
Abstract
MYC is one of the most widely studied proto-oncogenes.It belongs to the basic helix-loop-helix leucine zipper(bHLH-Zip)DNA-binding protein superfamily and functions by forming MYC-MAX heterodimer.MYC affects a variety of biological processes,such as protein synthesis,cell adhesion,proliferation,differentiation,cell cycle,metabolism,apoptosis,and angiogenesis.Due to its special structure and location,it is difficult to directly target MYC.The therapeutic strategy for MYC is the focus of research.This article will sys-tematically review the structure and functions of MYC gene and the research progress of its inhibitors,to provide new options for the treat-ment of tumor by targeting MYC.关键词
MYC基因/抑制剂/靶向治疗Key words
MYCgene/inhibitors/targeted therapy分类
医药卫生引用本文复制引用
徐冶..靶向MYC基因抗肿瘤研究进展[J].吉林医药学院学报,2024,45(4):241-245,5.
