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自发性气胸单孔胸腔镜手术后肺部并发症预测模型的构建OACSTPCD

Prediction model construction of pulmonary complications after single port thoracoscopic spontaneous pneumothorax operation

中文摘要英文摘要

目的:探讨自发性气胸单孔胸腔镜手术后肺部并发症预测模型的构建.方法:选取 2021 年 5 月至 2022 年 5 月行单孔胸腔镜手术的106 例自发性气胸患者,根据术后是否发生肺部并发症将患者分为并发症组(n=22)与无并发症组(n=84).对两组患者临床资料进行单因素与多因素分析,筛选出影响术后肺部并发症的危险因素,并构建列线图预测模型.结果:并发症组患者年龄、吸烟史、合并肺部疾病、胸膜粘连严重、肺大疱数量、术后24h疼痛分级、术中出血量高于无并发症组,术前白蛋白水平低于无并发症组.多因素Logistic回归分析结果显示,年龄≥50 岁(OR=1.240,95%CI=1.064~1.445)、合并肺部疾病(OR=26.154,95%CI=1.224~558.648)、胸膜粘连严重(OR=23.289,95%CI=2.940~184.520)、肺大疱数量>2个(OR=2.878,95%CI=1.787~4.633)是影响术后肺部并发症的独立危险因素(P<0.05).根据以上危险因素建立预测模型预测术后肺部并发症的受试者工作特征曲线下面积为 0.82(95%CI=0.756~0.874),敏感度与特异度分别为 82.33%与65.47%.结论:年龄、合并肺部疾病、胸膜粘连严重、肺大疱数量是影响自发性气胸单孔胸腔镜手术后肺部并发症的独立危险因素,根据其构建的列线图预测模型对术后肺部并发症的发生风险具有较好的预测价值.

Objective:To investigate the construction of prediction model of pulmonary complications in patients with spontane-ous pneumothorax after single port thoracoscopic surgery.Methods:From May 2021 to May 2022,106 patients with spontaneous pneu-mothorax who had undergone single port thoracoscopic surgery were selected and divided into complication group(n=22)and non-complication group(n=84)according to the occurrence of postoperative lung complications.The clinical data of the patients in two groups were analyzed by univariate and multivariate analysis,and the risk factors affecting postoperative pulmonary complications were screened out,and the prediction model was constructed by nomogram.Results:Age,smoking history,pulmonary disease,severe pleural adhesion,number of pulmonary bullae,pain grade 24 h after surgery,and intraoperative blood loss in the complication group were higher than those in the non-complication group,preoperative albumin level was lower.Multivariate logistic regression analysis showed that age≥50 years old(OR=1.240,95%CI=1.064~1.445),pulmonary disease(OR=26.154,95%CI=1.224~558.648),severe pleural adhesion(OR=23.289,95%CI=2.940~184.520)and the number of pulmonary bullae>2(OR=2.878,95%CI=1.787~4.633)were independent risk factors for postoperative pulmonary complications(P<0.05).The area under receiver operating charac-teristic curve of the predictive model established based on the above risk factors for predicting postoperative pulmonary complications was 0.82(95%CI=0.756~0.874),the sensitivity and specificity was 82.33%and 65.47%,respectively.Conclusions:Age,pul-monary disease,severe pleural adhesion,and the number of pulmonary bullae are independent risk factors for pulmonary complications after single port thoracoscopic spontaneous pneumothorax operation.The prediction model based on these factors has good predictive val-ue for predicting the risk of postoperative pulmonary complications.

王永平;王辉;郑翔;闻作川;田浩;陈鹏;刘冠群

北京市大兴区人民医院胸外血管外科,北京,102600

临床医学

自发性气胸胸腔镜检查单孔术后肺部并发症预测模型

Spontaneous pneumothoraxThoracoscopySingle portPostoperative pulmonary complicationsPrediction model

《腹腔镜外科杂志》 2024 (005)

321-325 / 5

10.13499/j.cnki.fqjwkzz.2024.05.321

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