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葡萄球菌性烫伤样皮肤综合征的研究进展

张睿 尤聪 李龙年 叶小英

赣南医学院学报2024,Vol.44Issue(6):617-621,5.
赣南医学院学报2024,Vol.44Issue(6):617-621,5.DOI:10.3969/j.issn.1001-5779.2024.06.013

葡萄球菌性烫伤样皮肤综合征的研究进展

Research progress of staphylococcal scaled skin syndrome

张睿 1尤聪 2李龙年 2叶小英2

作者信息

  • 1. 赣南医科大学第一临床医学院
  • 2. 赣南医科大学第一附属医院皮肤性病科 国家皮肤与免疫性疾病临床研究中心分中心建设单位,江西 赣州 341000
  • 折叠

摘要

Abstract

Staphylococcal scaled skin syndrome(SSSS)is a potentially life-threatening disorder and an acute epidermal exfoliation syndrome.The disease is caused by toxigenic strains of Staphylococcus aureus(S.aureus)which belongs to phage group Ⅱ and produces soluble toxin-exfoliative toxins.The diagnosis is mainly based on clinical manifestations,including erythroderma,bullae,desquamation with a scalded appearance,perioral crusting,positive Niskolsky sign,and absence of mucosal involvement.At present,the anti-S.aureus antibiotics are used for treatment of SSSS,including penicillinase-resistant penicillin,cephalosporin,vancomycin,clindamycin and other antibiotics.Both the incidence and the risk of complications and death of SSSS are increasing year by year.The research progress on SSSS in recent years is summarized in the present review to improve the knowledge of healthcare workers on SSSS.

关键词

葡萄球菌性烫伤样皮肤综合征/金黄色葡萄球菌/剥脱毒素/抗生素/治疗

Key words

Staphylococcal scaled skin syndrome/Staphylococcus aureus/Exfoliative toxins/Antibiotics/Treatment

分类

医药卫生

引用本文复制引用

张睿,尤聪,李龙年,叶小英..葡萄球菌性烫伤样皮肤综合征的研究进展[J].赣南医学院学报,2024,44(6):617-621,5.

基金项目

国家自然科学基金地区科学基金项目(81960566) (81960566)

赣南医学院学报

1001-5779

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