牙周炎患者牙周支持治疗对血细胞指标影响的回顾性研究OA北大核心CSTPCD

Objective This study aimed to investigate the effect of supportive periodontal therapy(SPT)on blood cell indicators in patients with periodontitis.Methods In accordance with the inclusion and exclusion criteria,patients who were diagnosed with periodontitis at Changsha Stomatological Hospital from January 2014 to March 2022 were included.On the basis of whether SPT was performed on patients or not,patients were divided into maintenance group(74 patients)and nonmaintenance group(76 patients)to compare the differences in blood cell indicators between the two groups.Re-sults After treatment,the neutrophil count(N),white blood cell count(WBC),platelet count(PLT),and systemic im-mune-inflammation index(SII)of the maintenance group decreased(P<0.05);the mean corpuscular hemoglobin concen-tration(MCHC),mean corpuscular volume(MCV),and mean platelet volume(MPV)increased(P<0.05);the hemoglobin(HGB)showed no significant change(P>0.05).The SII of the nonmaintenance group decreased,whereas the MPV and MCV increased(P<0.05).By comparing the changes in blood cell indicators,we found significant differences in WBC,N,PLT,SII,MCV,MCHC,and MPV between the two groups(P<0.05).During the 5-year follow-up period,a decreasing trend in WBC,N,PLT,and SII and an increasing trend in MCHC,MPV,and MCV in the maintenance group were observed.Conclusion Active SPT could improve the hematological parameters of patients,alleviate the immune and inflammatory imbalance,and benefit the maintenance and improvement of the treatment effect.