国际口腔医学杂志2024，Vol.51Issue(4)：416-424,9.DOI:10.7518/gjkq.2024037
壳聚糖治疗牙周病的研究进展
Research progress on chitosan in periodontal disease treatment
摘要
Abstract
Chitosan is the only naturally occurring cationic polysaccharide and has gradually become a focus of atten-tion in tissue engineering due to its good biocompatibility;biodegradability;antibacterial,anti-inflammatory,anticancer,and tissue repair activity;and great drug delivery capacity.Periodontal disease,as an inflammatory and destructive di-sease,has a high prevalence and significant impact on oral health and even systemic health.In this review,we summarize the role of chitosan in periodontal therapy,including its regenerative scaffolding;drug delivery;and antibacterial,anti-in-flammatory,and angiogenesis-promoting effects.We then analyze current issues and point out possible future directions for its development,aiming to provide solutions to problems encountered in periodontal disease treatment.关键词
牙周病/壳聚糖/多向支架/药物递送/抗菌Key words
periodontal disease/chitosan/multidirectional scaffold/drug delivery/antibacterial properties分类
医药卫生引用本文复制引用
温星悦,赵骏宇,赵崇钧,王贵欣,黄睿洁..壳聚糖治疗牙周病的研究进展[J].国际口腔医学杂志,2024,51(4):416-424,9.基金项目
National Natural Science Foundation of China(21978179,31800114) （21978179,31800114）
Sichuan University Innovation and Entrepreneurship Training Program under Grants(C2023122912) 国家自然科学基金面上项目(21978179,31800114) （C2023122912）
四川大学大学生创新创业训练计划(C2023122912) （C2023122912）
