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牙周炎与心力衰竭相关性的研究进展

刘诗礼 赵蕾

国际口腔医学杂志2024,Vol.51Issue(4):425-432,8.
国际口腔医学杂志2024,Vol.51Issue(4):425-432,8.DOI:10.7518/gjkq.2024059

牙周炎与心力衰竭相关性的研究进展

Progress of research on the correlation between periodontitis and heart failure

刘诗礼 1赵蕾1

作者信息

  • 1. 口腔疾病防治全国重点实验室 国家口腔医学中心 国家口腔疾病临床医学研究中心四川大学华西口腔医院牙周病科 成都 610041
  • 折叠

摘要

Abstract

Heart failure(HF)is a serious manifestation or terminal stage of various heart diseases,seriously affecting the physical and mental health of patients.Its etiology is explored through many aspects,among which the influence of in-flammation on the HF process is a scholarly research hotspot.Periodontitis is a destructive disease of periodontal soft and hard tissues caused by plaque biofilm and is one of the two major oral diseases.Periodontitis is reportedly associated sig-nificantly with cardiovascular disease(CVD).The relationship between periodontitis and HF and its mechanism remain in the initial stage of research.Periodontal pathogens and their toxic products can reportedly affect myocardial function di-rectly and indirectly,thereby affecting HF progression.This work provides a review of the progress of research on perio-dontitis and HF to provide some research ideas for the joint prevention and treatment of periodontitis and CVD.

关键词

心力衰竭/牙周炎/心肌重构/心肌细胞

Key words

heart failure/periodontitis/cardiac remodeling/cardiomyocyte

分类

医药卫生

引用本文复制引用

刘诗礼,赵蕾..牙周炎与心力衰竭相关性的研究进展[J].国际口腔医学杂志,2024,51(4):425-432,8.

基金项目

National Natural Science Foundation of China(81970944) (81970944)

Sichuan Provincial Natural Science Founda-tion of China(2023NSFSC0553) (2023NSFSC0553)

Chengdu Science and Technology Project(2021-YF05-01864-SN) 国家自然科学基金(81970944) (2021-YF05-01864-SN)

四川省自然科学基金(2023NSFSC0553) (2023NSFSC0553)

成都市科技项目(2021-YF05-01864-SN) (2021-YF05-01864-SN)

国际口腔医学杂志

OA北大核心CSTPCD

1673-5749

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