国际老年医学杂志2024，Vol.45Issue(4)：444-447,4.DOI:10.3969/j.issn.1674-7593.2024.04.011
立体定向微创手术治疗对老年脑胶质瘤患者免疫水平及日常生活能力的影响
Effect of Stereotactic Minimally Invasive Surgery on Immune Level and Activities of Daily Living in Elderly Patients with Glioma
摘要
Abstract
Objective To investigate the effect of stereotactic minimally invasive surgery on immune level and activities of daily living in elderly patients with glioma.Methods Ninety elderly patients with glioma admitted to the First Affiliated Hospital of Harbin Medi-cal University from March 2020 to February 2022 were selected as the study subjects and divided into two groups according to the random number table,45 cases for each group.The control group was treated with conventional craniotomy and the observation group was treated with stereotactic minimally invasive surgery.The clinical efficacy,activities of daily living(ADL)score,National Institutes of Health Stroke Scale(NIHSS)score,peripheral blood immune parameters T helper(Th)1,Th2 and Th17 levels were compared between the two groups.Results The overall response rate in the observation group was higher than that in the control group.The recurrence rate at 1 year after sur-gery was lower than that in the control group.After treatment,the ADL score in the observation group was higher than that in the control group,the NIHSS score was lower than that in the control group,the Th1 level was higher than that in the control group,and the Th2 and Th17 levels were lower than those in the control group.The differences were statistically significant(P<0.05).Conclusion Stereotactic minimally invasive surgery is effective in the treatment of glioma in the elderly,not only improving the immune function indicators and neuro-logical deficits,but also helping to improve the activities of daily living,reduceing short-term recurrence rate.关键词
立体定向微创手术/脑胶质瘤/神经功能缺损/日常生活能力/免疫功能Key words
Stereotactic minimally invasive surgery/Glioma/Neurological deficit/Activities of daily living/Immune function引用本文复制引用
王浩然,石长斌,杜文众,杨猛,刘文,邓文佳..立体定向微创手术治疗对老年脑胶质瘤患者免疫水平及日常生活能力的影响[J].国际老年医学杂志,2024,45(4):444-447,4.基金项目
黑龙江省重点研发计划指导类项目(GZ20210157) （GZ20210157）
