急性缺血性脑卒中患者早发型癫痫发作的危险因素分析OACSTPCD

Objective To analyze the related risk factors for early-onset epilepsy of patients with acute ischemic stroke,and provide information for clinical prevention and treatment.Methods Eighty patients with early-onset epilepsy after acute ischemic stroke who were hospitalized from September 2019 to September 2023 were selected as the observation group,and 80 acute ischemic stroke patients without epilepsy who were hospitalized at the same time were randomly selected as the control group.The general data,bad habit,basic diseases,serum electrolyte,homocysteine,neuron-specific enolase,location of infarction,the number of infarcts,the cause of infarction,and the NIHSS score at admission were compared between the two groups.Results There were statistically significant differences in infarct location,infarct number,infarct etiology,homocysteine,neuronal enolase and NIHSS scores between the two groups(P<0.05).Multivariate Logistic regression analysis showed that cerebral cortical infarction(OR=7.924,P<0.001),cardiogenic cerebral infarction(OR=11.763,P<0.001),serum homocysteine(OR=4.980,P<0.001)and neuronal enolase(OR=4.674,P<0.001)were associated with early-onset epilepsy in CIS patients.Conclusion The cerebral cortical infarction,cardiogenic cerebral infarction,high levels of serum homocysteine and neuron-specific enolase are independent risk factors for early-onset epilepsy after acute ischemic stroke.