中国实用神经疾病杂志2024，Vol.27Issue(7)：809-815,7.DOI:10.12083/SYSJ.231289
辽宁省重症肌无力患者临床特征分析
Analysis of clinical features of patients with myasthenia gravis in Liaoning province
摘要
Abstract
Objective To investigate the clinical features of myasthenia gravis(MG)in Liaoning province.Methods Retrospective count and analysis were conducted to analyze 385 cases treated in Liaoning Hospital of Traditional Chinese Medicine from September 2019 to July 2021,including gender,onset age,initial symptom,thymus condition,etc.Results Compared with previous reports in other regions,MG in Liaoning province had some differences,male∶female=1∶1.41,average age of onset was(49.78±18.58)years old,and there were two peaks of onset,75.06%of the initial symptom were reflected in ocular muscles.The onset age of thymoma MG was generally later than thymoma hyperplasia(P=0.003).MG patients with thymoma pathological classification of type B was more likely to involve respiratory muscles(P=0.030).Type B1 and B2 were prone to myasthenia crisis(P=0.001),29.9%thymoma patients living in mining counties,while 20.60%of patients from non-mining counties.The incidence of MG with other autoimmune diseases was 9.09%,and with vitiligo was 2.60%.Conclusion The differences between our research and foreign reports about this study are significant,which may be related to geography,environment and ethnicity.A full and comprehensive understanding of the clinical differences will be helpful for diagnosis,treatment and prognosis.关键词
重症肌无力/临床特征/自身免疫疾病/胸腺瘤/肌无力危象Key words
Myasthenia gravis/Clinical features/Autoimmune diseases/Thymoma/Myasthenic crisis分类
医药卫生引用本文复制引用
张一博,乔文军,李兆卿,刘榴,丁佳..辽宁省重症肌无力患者临床特征分析[J].中国实用神经疾病杂志,2024,27(7):809-815,7.基金项目
辽宁省重症肌无力诊疗重点实验室项目(编号:2020JH13/10200022) （编号:2020JH13/10200022）
