摘要
Abstract
Objective To understand the current status of economic toxicity in lymphoma chemotherapy patients and analyzing its influencing factors,so as to provide insights for improving patient prognosis.Methods A total of 140 patients undergoing lymphoma chemotherapy were enrolled in this study.The clinical data of patients were collected.A cross-sectional survey was conducted using the patient-reported outcomes measurement information system-economic toxicity composite score(PROMIS-EC)to assess the economic burden.Multivariate linear regression analysis was applied to investigate the factors associated with economic toxicity in lymphoma patients.Results The total economic toxicity score for lymphoma chemotherapy patients was(20.27±6.99)points,with 106 cases(75.71%)experiencing economic toxicity.Differences in economic toxicity scores were found among patients of different ages,marital statuses,types of medical insurance,current employment status,pre-diagnosis employment status,number of children,financial independence of children,average monthly household income,disposable savings,use of novel anti-tumor drugs,and those undergoing transplantation or immunotherapy,with statistical significance(all P<0.05).Multivariate linear regression results indicated that the new rural cooperative medical system insurance,unemployment status prior to diagnosis,limited disposable family savings,use of novel antitumor drugs,and undergoing transplantation or immunotherapy were all risk factors for economic toxicity in lymphoma chemotherapy patients(all P<0.05),accounting for 51.3%of the total variability.Conclusions Most lymphoma chemotherapy patients experience economic toxicity,primarily associated with the type of medical insurance,employment status,and financial situation.It is recommended that clinicians assess patients'levels of economic toxicity early on and select personalized treatment plans to improve prognosis.关键词
淋巴瘤/化疗/经济毒性/影响因素/疾病负担Key words
lymphoma/chemotherapy/economic toxicity/influencing factor/burden of disease分类
医药卫生
