临床小儿外科杂志2024，Vol.23Issue(6)：561-566,6.DOI:10.3760/cma.j.cn101785-202203078-010
先天性脊柱侧凸半椎体畸形患儿围手术期血清C-反应蛋白变化及影响因素研究
Changes and predictors for perioperative C-reactive protein in children with congenital scoliosis hemi-vertebral deformity
摘要
Abstract
Objective To explore the changes and predictors for perioperative C-reactive protein(CRP)in children with congenital scoliosis hemivertebral deformity and summarize the relevant clinical experiences.Methods From October 2020 to October 2021,the clinical data were reviewed for 101 children with congenital scoliosis hemivertebral deformity.Posterior hemivertebra resection and internal fixation were performed.Factors including age,gender,height,weight,Stamp score,blood glucose,fasting time,preoperative Cobb angle,correc-tion rate,operated segment,osteotomy findings,operative duration and laboratory examinations were analyzed by linear regression.And the changes and predictors of CRP were examined during perioperative period.Results All operations were completed successfully.There were 43 boys and 58 girls with an age range of(6.4±3.5)years.Operative duration was(199.2±68.4)min with an average of 3 operated segments and scoliosis correction rate 90.6％.Multivariable linear regression analysis indicated that an elevated level of post-operative CRP was associated with age,preoperative Cobb angle,operative duration and number of operated seg-ments.Operative segment ≥4,operative duration ≥157 min and preoperative Cobb angle ≥27° hinted at a higher level of CRP(all P＜0.05).Conclusions Children with severe deformity,more fused levels and lon-ger operative duration tend to carry a greater risk of a higher postoperative level of CRP.关键词
脊柱侧凸,先天性/矫形外科手术/围手术期/C反应蛋白质/影响因素分析Key words
Scoliosis,Congenital/Orthopedic Procedures/Perioperative Period/C-Reactive Protein/Root Cause Analysis引用本文复制引用
张瀚文,祁新禹,刘昊楠,赵梦奇,郭东,白云松,李承鑫,张学军..先天性脊柱侧凸半椎体畸形患儿围手术期血清C-反应蛋白变化及影响因素研究[J].临床小儿外科杂志,2024,23(6):561-566,6.基金项目
北京市自然科学基金(1222095)和新疆维吾尔自治区重点研发任务专项项目(2023B03018) Beijing Natural Science Foundation(L222095)& Key R&D Program of Xinjiang(2023B03018) （1222095）
