临床眼科杂志2024，Vol.32Issue(3)：279-283,5.DOI:10.3969/j.issn.1006-8422.2024.03.020
干燥综合征型干眼发病机制研究进展
Progress in the study of the pathogenesis of dry eye of dry syndrome type
张越鑫 1李锦玉 1郝彦淞 1姜善好2
作者信息
- 1. 264003 滨州,滨州医学院第二临床学院
- 2. 264100 滨州,滨州医学院烟台附属医院
- 折叠
摘要
Abstract
Dry eye is a kind of ocular surface disease with complex pathogenesis and multi-factor influence.The main characteristics of dry eye are ocular discomfort and visual impairment caused by persistent tear film instability.Sjögren's syndrome is a systemic autoimmune disease that mainly involves exocrine glands such as lacrimal and salivary glands.Only 10%of dry eyes are caused by Sjögren's syndrome,which causes severe eye irritation and visual impairment.Currently,studies on dry eye mainly focus on metaromian gland dysfunction dry eye with a high incidence,while there are few studies on the pathogenesis of Sjögren's type dry eye.This paper will review the pathogenesis of Sjögren's type dry eye from the aspects of neural abnormalities of lacrimal gland and cornea,changes in proteomic characteristics,and elevated osman pressure of tears.It is hoped to provide a new direction for subclinical prevention and treatment of Sjögren's syn-drome type dry eye.关键词
干眼/干燥综合征/神经异常/蛋白质组学特征的改变/泪膜渗透压升高Key words
Dry eyes/Sjögren's syndrome/Neuropathy/Changes in proteomic characteristics/Elevated osmotic pressure of tear film引用本文复制引用
张越鑫,李锦玉,郝彦淞,姜善好..干燥综合征型干眼发病机制研究进展[J].临床眼科杂志,2024,32(3):279-283,5.
