宁夏大学学报(自然科学版)2024,Vol.45Issue(2):149-154,6.
金属有机框架UiO-66封装硼酸碳点荧光材料用于黄芩苷检测
Metal-Organic Framework UiO-66 Encapsulates Boric Acid Carbon Dot Fluo-rescent Material for Baicalin Detection
摘要
Abstract
In this paper,UiO-66 metal-organic frameworks(MOFs)encapsulated woth boric acid carbon dots(PBA-CDs)were synthesized as high-efficiency fluorescent probes(UiO-66/PBA-CDs)for the specific recog-nition of target molecules,and were used for the sensitive detection of baicalin(BAI).Incorporating PBA-CDs into UiO-66 with high specific surface area enabled the capture and recognition of BAI,thereby avoiding the agglomeration quenching of carbon dots and improving the sensitivity of fluorescence detection.In order to ver-ify the selectivity of UiO-66/PBA-CDs,comparative experiments were conducted with other drug molecules and amino acids containing o-dihydroxyl groups,confirming the good selectivity of UiO-66/PBA-CDsfor BAI.Furthermore,the fluorescence quantitative method demonstrated a satisfactory linear detection range of 10 to 70 nmol/L.The quantitative analysis of BAI content in wolfberry using the standard addition method yielded accu-rate results with high recovery rates,affirming the potential of the fluorescent probe developed in this study for the detection of BAI in complex drugs.关键词
硼酸碳点/金属有机框架/荧光探针/黄芩苷Key words
boronic acid carbon dots/metal-organic framework/fluorescent probe/Baicalin分类
化学化工引用本文复制引用
唐晓凡,唐荣宏,卜春苗..金属有机框架UiO-66封装硼酸碳点荧光材料用于黄芩苷检测[J].宁夏大学学报(自然科学版),2024,45(2):149-154,6.基金项目
北方民族大学青年人才培育基金资助项目(2021KYQD30) (2021KYQD30)
国家自然科学基金资助项目(22064013) (22064013)
北方民族大学2023年大学生区级创新训练计划项目(S202311407037) (S202311407037)