皮肤性病诊疗学杂志2024，Vol.31Issue(6)：427-431,5.DOI:10.3969/j.issn.1674-8468.2024.06.010
疱疹样天疱疮1例
A case of herpetiform pemphigus
摘要
Abstract
A case of herpetiform pemphigus is reported.A 76-year-old man suffered from ery-thema,blisters and pruritus on the trunk and extremities for 10 months.Dermatological examina-tion revealed a large number of erythemas,papules,hyperpigmented spots and isolated pinpoint-to-green bean-sized blisters over the erythemas on the trunk and limbs.The blisters appeared hem-ispheric,with thick walls and clear fluid.Nikolsky's sign was negative.Some blisters were rup-tured,with erosive surface.Skin histopathology showed epidermal blisters containing eosinophils and neutrophils,and perivascular infiltrates of lymphohistiocytes and eosinophils in the superficial dermis.Direct immunofluorescence showed reticular deposition of IgG and C3 in the epidermis.Diagnosis was herpetiform pemphigus.The patient was treated with methylprednisolone,cyclo-phosphamide,rupatadine,ketotifen,and topical compound clobetasol propionate ointment.Nine days later,most of the blisters dried up,and the patient was discharged,without recurrence dur-ing 6-month telephone follow-up.关键词
疱疹样天疱疮/糖皮质激素Key words
herpetiform pemphigus/glucocorticoids引用本文复制引用
刘雅芹,陈留鑫,谢映霞,祝瑶,邓诗音,蔡艳霞..疱疹样天疱疮1例[J].皮肤性病诊疗学杂志,2024,31(6):427-431,5.基金项目
广东医科大学附属医院临床研究(LCYJ2019C008) （LCYJ2019C008）
