实用医学杂志2024，Vol.40Issue(13)：1840-1845,6.DOI:10.3969/j.issn.1006-5725.2024.13.013
达芬奇机器人辅助胸腔镜在小儿纵隔肿瘤切除术中使用的可行性及安全性
Feasibility and safety of Da Vinci robotic-assisted thoracoscopy in pediatric mediastinal tumor resection
摘要
Abstract
Objective This study aims to investigate the feasibility and safety of Da Vinci robotic-assisted thoracoscopy for resecting mediastinal tumors in pediatric patients.Methods From November 2020 to June 2023,a total of 80 pediatric patients undergoing mediastinal tumor resection at Wuhan Children's Hospital were randomly assigned into two groups,with each group consisting of 40 participants.The control group underwent conventional thoracoscopy,while the observation group underwent Da Vinci robotic-assisted thoracoscopy.This study aimed to compare perioperative indicators between the two groups and establish learning curves based on surgical duration and intraoperative blood loss.Additionally,it assessed levels of pain mediators and stress response markers before surgery and at 24 hours post-surgery,as well as postoperative complications.Inflammatory marker levels were evaluated one month after surgery,and the children's quality of life was measured using the Pediatric Quality of Life Inventory(PedsQL)Generic Core Scales before surgery and one month post-surgery.Results The surgical duration for the observation group and the control group was(1.76±0.33)hours and(2.82±0.62)hours,respectively,and the intraoperative blood loss was(49.83±6.39)mL and(71.55±8.19)mL,respectively.Furthermore,the post-operative drainage time,drainage volume,and hospital stay for the observation group were all lower than those for the control group(P<0.05).After surgery,the levels of BK,5-HT,NPY,and PGE2 in the observation group were(8.06±1.06)mg/L,(170.20±13.21)ng/L,(201.82±13.52)mg/L,and(241.82±15.32)ng/L,respectively,indicating lower levels of pain mediators,stress response markers,and inflammatory factors compared to the control group(P<0.05).he overall incidence of complications was 2.50%in the observation group as opposed to 20.00%in the control group.Moreover,there was a statistically significant improvement in quality of life after surgery within the observation group when compared to that within the control group(P<0.05).Conclusion Da Vinci robotic-assisted thoracoscopy demonstrates enhanced feasibility and safety in pediatric mediastinal tumor resection,thereby justifying its clinical promotion.关键词
达芬奇机器人/胸腔镜/纵隔肿瘤/应激反应Key words
Da Vinci robot/thoracoscopy/mediastinal tumor/stress response分类
医药卫生引用本文复制引用
刘慧芳,汪力,董璠,胡超群,陈德美,范丽..达芬奇机器人辅助胸腔镜在小儿纵隔肿瘤切除术中使用的可行性及安全性[J].实用医学杂志,2024,40(13):1840-1845,6.基金项目
湖北省自然科学基金项目(编号:2021CFB203) （编号:2021CFB203）
