实用医学杂志2024，Vol.40Issue(13)：1874-1878,5.DOI:10.3969/j.issn.1006-5725.2024.13.019
血尿素氮对脓毒性休克患者院内死亡风险的预测价值
Predictive value of blood urea nitrogen for in-hospital death risk in patients with septic shock
摘要
Abstract
Objective To investigate the relationship and predictive value of blood urea nitrogen(BUN)levels with the risk of in-hospital mortality in patients with septic shock.Methods Clinical data of 328 patients diagnosed with septic shock from January 1,2018 to September 30,2023 in Shenzhen Second People's Hospital were retrospectively collected.The primary outcome indicator was in-hospital death in patients with septic shock.Simple logistic regression analyses was used to explore the correlation between BUN and in-hospital death in patients with septic shock;multiple logistic regression analyses model was used to explore the quantitative relationship between BUN and in-hospital death in septic shock,sensitivity analyses was utilized to test the stability of the results.Results Simple logistic regression analyses suggested that BUN was a risk factor for in-hospital mortality in patients with septic shock.Multiple logistic regression analyses showed a positive correlation between BUN and in-hospital mortality in patients with septic shock:the risk of in-hospital mortality in patients with septic shock was increased by 3.3%for every 1 mmol/L increase in BUN(OR=1.033,P<0.01);after adjusting for different vari-ables,the risk of in-hospital death increased by 2.9%(OR=1.029,P<0.05)and 3.2%(OR=1.032,P<0.05)for each 1 mmol/L increase in BUN,respectively.Sensitivity analyses further confirmed the stability of the results(OR=1.04,P<0.05).Conclusion There is a positive correlation between BUN levels and in-hospital death in patients with septic shock,and it has a predictive value for the risk of in-hospital death in patients with septic shock.关键词
脓毒性休克/血尿素氮/死亡风险/预测Key words
septic shock/blood urea nitrogen/risk of mortality/predict分类
医药卫生引用本文复制引用
庞婷,韩勇,周力,谢莉惠,雷景恒,邓哲..血尿素氮对脓毒性休克患者院内死亡风险的预测价值[J].实用医学杂志,2024,40(13):1874-1878,5.基金项目
深圳市科技计划(编号:JCYJ20180228163014668) （编号:JCYJ20180228163014668）
广东省高水平医院建设项目深圳市第二人民医院临床研究基金(编号:20223357005,2023xgyj3357002) （编号:20223357005,2023xgyj3357002）
