MER联合Lead-DBS在帕金森病患者术后程控中的应用研究OA

Objective To explore the application effect of microelectrode recording(MER)combined with multimodal image fusion technology(Lead-DBS)in postoperative programming of patients with Parkinson's disease.Methods A total of 60 patients with Parkinson's disease treated in The 988th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army from October 2018 to August 2023 were selected.They were randomly divided into the control group and the observation group.The control group patients were programmed one by one according to the consensus of deep brain stimulation(DBS)experts,and the observation group patients were programmed according to MER combined with postoperative Lead-DBS multimodal image fusion technology.The operation time,postoperative symptom improvement,quality of life score,negative emotions,and incidence of complications in the two groups were compared.Results The operation time of the observation group was less than that of the control group,with a statistically significant difference(P＜0.05).Before intervention,there was no statistically significant difference in Parkinson's symptom score,Parkinson's disease quality of life score,negative emotion score,and incidence of complications between the two groups(P＞0.05).After intervention,the Parkinson's symptom score,Parkinson's disease quality of life score,negative emotion score,and incidence of complications in the observation group were all lower than those in the control group,with statistically significant differences(P＜0.05).Conclusion The intraoperative MER combined with postoperative Lead-DBS multimodal image fusion technology,combined with the patient's symptoms to selectively choose the on-point method,has a high feasibility,can improve the operation efficiency,improve the patient's prognosis,and has good safety.