持续性高过载下人脑的多孔弹性响应OA北大核心CSTPCD

Sustained high overloads often acting during aerospace flights can significantly affect the passenger brain function dependent on the mechanical behavior of brain tissue and highly correlated with load characteris-tics.To predict the mechanical responses of human brain under sustained high overloads,the poroelastic con-stitutive model was adopted to characterize the mechanical behaviors of brain tissue.Built on an idealized 1D multi-layer structural model for human heads,the poroelastic control equation and the state transfer matrix for the brain tissue were derived.Through the Laplace transform and its inverse transform,the spatiotemporal dis-tribution of the intracranial fluid pressure,the intracranial fluid seepage velocity,the brain tissue effective stress,and the brain tissue displacement were obtained.The results indicate that,the intracranial fluid infiltra-tion has a significant impact on the responses of the brain tissue under sustained high overloads.The present work emphasizes the appropriateness and necessity of using poroelastic constitutive models to describe the me-chanical behavior of brain tissue,providing important theoretical insights for the study of brain biomechanics under extreme load conditions.