中国听力语言康复科学杂志2024，Vol.22Issue(4)：346-350,365,6.DOI:10.3969/j.issn.1672-4933.2024.04.004
人工耳蜗植入术后电诱发听性脑干反应的电生理特征与参数优化研究
Electrophysiological Characteristics and Parameter Optimization of Electrically Evoked Auditory Brainstem Responses after Cochlear Implantation
摘要
Abstract
Objective This study aimed to investigate the effects of different test parameters on the waveforms of electrically evoked auditory brainstem responses(EABR),to select the optimized EABR test parameters after cochlear implantation,and to explore the relationship between EABR and behavioral test results after cochlear implantation.Methods The study included 17 Nurotron cochlear implant recipients.The characteristics of the EABR,such as the occurrence rate,threshold,and latency of wave V,were recorded and analyzed for stimulation at different electrode positions,pulse intervals,and alternating/non-alternating biphasic pulse currents.The correlation between EABR threshold and behavioral T and C values at different electrode positions was also analyzed.Results The threshold of EABR wave V at the apex of the cochlea(90.58±27.39 CU)was significantly lower than that at the middle turn(106.98±15.66 CU).The latency of wave V at the apex of the cochlea(4.47±0.357 ms)was significantly shorter than that at the middle turn(4.72±0.335 ms).The amplitude of the electrical artifact using alternating biphasic pulse current(9.40±12.35 μV)was significantly smaller than that using non-alternating pulse(19.49±15.12μV).The threshold of EABR at the apex of the cochlea was significantly correlated with the T value and C value of the behavioral test.Conclusion The stimulation electrode position and pulse current type both affect the waveforms of EABR.The apex stimulation is more likely to evoke the ideal EABR waveforms than the middle turn,and the use of alternating biphasic pulse current stimulation can effectively reduce the impact of electrical artifacts.The EABR threshold can provide a reference for the activation and mapping after cochlear implantation.关键词
电诱发听性脑干反应/人工耳蜗植入/脉冲间隔/电极位置/交替双相脉冲电流Key words
Electrically evoked auditory brainstem response/Cochlear implantation/Pluse interval/Electrode position/Alternating biphasic pulse currents分类
医药卫生引用本文复制引用
王宇,林以鹏,鲁兆毅,潘滔,银力,高珊仙..人工耳蜗植入术后电诱发听性脑干反应的电生理特征与参数优化研究[J].中国听力语言康复科学杂志,2024,22(4):346-350,365,6.基金项目
北京大学第三医院海淀创新转化专项(HDCXZHKC2022211) （HDCXZHKC2022211）
2023年海淀区卫生健康发展科研培育计划《人工耳蜗植入儿童的听觉可塑性研究》(HP2023-11-501004) （HP2023-11-501004）
