艾司氯胺酮联合舒芬太尼对全身麻醉腹腔镜术后患者复苏效果的影响OA
Influence of Esketamine Combined with Sufentanil on Recovery Effect in Patients after Operative Laparoscopy under General Anesthesia
目的:探讨艾司氯胺酮联合舒芬太尼对全身麻醉腹腔镜手术患者术后复苏效果的影响.方法:选取 2022 年 1 月—2023 年 6 月在上饶市人民医院行全身麻醉腹腔镜手术患者 98 例,根据患者入院时间,将 2022 年 1-10 月收入患者纳为对照组(n=49),2022 年 11 月—2023 年 6 月收入患者纳为观察组(n=49).两组均进行全身麻醉,对照组在诱导开始时采用舒芬太尼,观察组在诱导开始时采用艾司氯胺酮联合舒芬太尼.比较两组围手术期指标、血流动力学、疼痛评分和不良事件发生率.结果:观察组气管导管拔出时间、呼吸恢复时间、睁眼时间均早于对照组,拔管后经皮动脉血氧饱和度(SpO2)高于对照组(P<0.05);拔管后,两组心率(HR)、舒张压(DBP)和平均动脉压(MAP)比较,差异均无统计学意义(P>0.05);拔管后,两组收缩压(SBP)和脑电双频指数(BIS)均高于拔管前,且观察组SBP低于对照组,BIS高于对照组(P<0.05);术后 30 min和 1、6 h,观察组视觉模拟评分法(visual analogue scale,VAS)评分均低于对照组(P<0.05);两组不良事件发生率比较,差异无统计学意义(P>0.05).结论:在全身麻醉诱导时,采用艾司氯胺酮联合舒芬太尼,可减轻腹腔镜术后患者疼痛,提高复苏效果,稳定血流动力学.
Objective:To explore the influence of Esketamine combined with Sufentanil on recovery effect in patients after operative laparoscopy under general anesthesia.Method:A total of 98 patients who underwent operative laparoscopy under general anesthesia in Shangrao People's Hospital from January 2022 to June 2023 were selected.Patients admitted from January to October 2022 were included in the control group(n=49),and patients admitted from November 2022 to June 2023 were included in the observation group(n=49).Both groups underwent general anesthesia,the control group received Sufentanil at the beginning of induction,and the observation group received Esketamine combined with Sufentanil at the beginning of induction.Perioperative indexes,hemodynamics,pain scores and incidence of adverse events were compared between the two groups.Result:Tracheal tube extraction time,respiratory recovery time and eye opening time in observation group were earlier than those in control group,and percutaneous arterial blood oxygen saturation(SpO2)after extubation in observation group was higher than that in control group(P<0.05).After extubation,there were no significant differences in heart rate(HR),diastolic blood pressure(DBP)and mean arterial pressure(MAP)in both groups(P>0.05).After extubation,systolic blood pressure(SBP)and bispectral index(BIS)of the two groups were higher than those those before extubation,and the SBP of the observation group was lower than that of the control group,BIS was higher than that of the control group(P<0.05).The visual analogue scale(VAS)scores of the observation group at 30 min and 1 and 6 h after surgery were lower than those of the control group(P<0.05).There was no significant difference in the incidence of adverse events between the two groups(P>0.05).Conclusion:During general anesthesia induction,Esketamine combined with Sufentanil can reduce the pain,improve the recovery effect and stabilize the hemodynamics of patients after operative laparoscopy.
叶镇远;缪倩;顾志伟;柴世权
上饶市人民医院麻醉科 江西 上饶 334000
艾司氯胺酮舒芬太尼腹腔镜手术全身麻醉麻醉复苏
EsketamineSufentanilOperative laparoscopyGeneral anesthesiaAnesthesia recovery
《中国医学创新》 2024 (017)
19-23 / 5
上饶市指导性科技计划项目(2022CZDX12)
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