中国美容医学2024，Vol.33Issue(7)：176-180,5.
肿瘤免疫编辑在黑素瘤肿瘤微环境中的研究进展
Research Progress of Tumor Immunoediting in the Tumor Microenvironment of Melanoma
摘要
Abstract
Melanoma is one of the most immunogenic forms of human cancer,rendering it particularly susceptible to immunotherapy,therefore,immunotherapy has become the most potential research and application field of melanoma.However,like most tumors,melanoma obtains inhibitory mechanisms through various pathways and has complex interactions with various components of the human immune system,allowing tumor cells to escape the surveillance of the immune system and ultimately leading to the development and metastasis of melanoma.In recent decades,great advances have been made in the in-depth study of melanoma-associated forming cells,immune cells,and related molecules,leading to the development and approval of several immunotherapy drugs that benefit some patients with advanced and metastatic melanoma.But the immunobiology of melanoma is still inadequate.Here,from the perspective of immunoediting,this paper reviews the evolution of the immune system and related cells during the occurrence and development of melanoma,reviews and integrates the existing knowledge of melanoma specific immunity,in order to have a wider application in the treatment of melanoma patients and find more effective therapies.关键词
黑素瘤/肿瘤微环境/免疫编辑/T细胞/B细胞/树突状细胞/自然杀伤细胞Key words
melanoma/tumor microenvironment/immunoediting/T cells/B cells/natural killer cells/dendritic cells分类
医药卫生引用本文复制引用
侯敏杰,段育任,裴洁,王小兵..肿瘤免疫编辑在黑素瘤肿瘤微环境中的研究进展[J].中国美容医学,2024,33(7):176-180,5.基金项目
山西省基础研究计划(编号:202103021223412) （编号:202103021223412）
