摘要
Abstract
Objective:To investigate the effect of Dexmedetomidine combined with Ropivacaine femoral nerve block and lateral femoral cutaneous nerve block in knee joint replacement.Method:A total of 82 patients intending to undergo knee arthroplasty admitted to Pingxiang Hospital of Traditional Chinese Medicine from June 2020 to June 2023 were selected and divided into observation group and routine group according to random number table method,with 41 cases in each group.The observation group received femoral nerve block and lateral femoral cutaneous nerve block with Dexmedetomidine and Ropivacaine,while the conventional group received Ropivacaine femoral nerve block and lateral femoral cutaneous nerve block.Operation-related indexes,hemodynamics,visual analogue scale(VAS)score and adverse reactions were compared between the two groups.Result:There were statistically significant differences in HR time,inter-group and interaction between the two groups(Ftime=9.654,Ptime=0.000,Fgroup=8.975,Pgroup=0.000,Finteraction=9.041,Pinteraction=0.000);the differences in MAP time,inter-group and interaction between the two groups were statistically significant(Ftime=10.231,Ptime=0.000,Fgroup=8.231,Pgroup=0.000,Finteraction=8.635,Pinteraction=0.000);HR and MAP of the observation group during prosthetic installation(T2)and tracheal catheter removal 5 min(T3)were lower than those of the conventional group(P<0.05).There were significant differences in VAS score time,inter-group and interaction between the two groups(Ftime=9.432,Ptime=0.000,Fgroup=9.342,Pgroup=0.000,Finteraction=8.321,Pinteraction=0.000).The VAS scores of the observation group at 3,9,12 and 24 h after surgery were lower than those of the conventional group,the differences were statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(x2=0.105,P=0.746).Conclusion:Dexmedetomidine combined with Ropivacaine femoral nerve block and lateral femoral cutaneous nerve block can stabilize hemodynamic indexes in knee joint replacement,have significant analgesic effect,reduce stress response,and have good safety.关键词
膝关节置换术/右美托咪定/罗哌卡因/股神经阻滞/股外侧皮神经阻滞/视觉模拟评分法Key words
Knee joint replacement/Dexmedetomidine/Ropivacaine/Femoral nerve block/Lateral femoral cutaneous nerve block/Visual analogue scale
