中国实用外科杂志2024，Vol.44Issue(6)：644-648,5.DOI:10.19538/j.cjps.issn1005-2208.2024.06.09
甲状腺癌远处转移的临床病理特征及危险因素
Clinicopathological characteristics and risk factors of distant metastasis in thyroid cancer
摘要
Abstract
Objective Patients with distant metastasis of thyroid cancer(TCDM)often have a poor prognosis,which is the main cause of cancer-related death of thyroid cancer.Many factors affect TCDM.Including children and adolescents,elderly patients,male patients,larger tumor diameter(maximum tumor diameter≥4 cm),thyroid capsule invasion,lymph node metastasis(more number,larger diameter),and poorly differentiated pathological types such as medullary thyroid cancer,poorly differentiated thyroid carcinoma,anaplastic thyroid carcinoma,etc.BRAFV600E and TERT promoter mutations are risk factors for distant metastasis of papillary thyroid carcinoma and anaplastic thyroid carcinoma,RET fusion gene and NTRK fusion gene mutations are risk factors for distant metastasis of differentiated thyroid cancer in children and adolescents,and RAS gene mutations are risk factors for distant metastasis of MTC.In the diagnosis and treatment of thyroid cancer,the high-risk factors of distant metastasis of thyroid cancer should be comprehensively considered,and more strict diagnosis and treatment plans should be formulated to improve the survival time of patients with distant metastasis of thyroid cancer.关键词
甲状腺癌/远处转移/临床病理特征/危险因素Key words
thyroid cancer/distant metastasis/clinicopatholog-ical characteristics/risk factors分类
医药卫生引用本文复制引用
殷德涛,李红强..甲状腺癌远处转移的临床病理特征及危险因素[J].中国实用外科杂志,2024,44(6):644-648,5.基金项目
河南省自然科学基金面上项目(No.222300420568) （No.222300420568）
河南省医学科技攻关重大计划项目(No.SBGJ202101014) （No.SBGJ202101014）
河南省中医药研究重大专项(No.20-21ZYZD14) （No.20-21ZYZD14）
河南省中青年医学科技创新领军人才项目(No.YXKC2020015) （No.YXKC2020015）
