中国医学前沿杂志（电子版）2024，Vol.16Issue(6)：38-43,6.DOI:10.12037/YXQY.2024.06-07
肥胖对体外冲击波治疗膝骨关节炎疗效的影响
Impact of obesity on the efficacy of extracorporeal shockwave therapy in knee osteoarthritis
摘要
Abstract
Objective To investigate the effect of obesity on the efficacy of extracorporeal shockwave therapy(ESWT)in the treatment of knee osteoarthritis(KOA).Methods A total of 123 patients with KOA were selected including 38 males and 85 females,with the mean age of(59.36±5.69)years old;and disease duration of(14.92±6.9)months.Patients were divided into normal BMI group(BMI<25 kg/m2)and obese group(BMI≥25 kg/m2).All patients received ESWT once a week for 8 weeks.The visual analog scale(VAS),Lequesne score,and Western Ontario and McMaster University Osteoarthritis Index(WOMAC)were compared between the two groups before treatment,after the 2nd week of treatment and after the 8th week of treatment,in order to evaluate the patients'pain and functional improvemen.t Results There was no significant difference in VAS score between the two groups before treatmen.t After 2 weeks of treatment,VAS pain score(2.40±0.79)in the obese group was better than that in the normal group(3.28±1.17)(P<0.01).Lequesne score of obesity group(4.40±2.54)was better than that of normal group(5.81±2.58)(P<0.01).The pain index and function index of WOMAC score in the obese group(6.76±2.58,21.14±8.59)were better than those in the normal group(7.98±2.24,25.91±8.09).After 8 weeks of treatment,VAS pain score of the normal group(2.27±1.44)was significantly improved compared with that of the obese group(1.63±0.85)(P<0.01).Lequesne score of the normal group(4.47±2.76)was significantly improved compared with that of the obese group(3.09±1.68)(P<0.01).The pain index,stiffness index and function index in WOMAC score after 8 weeks of treatment were(5.00±2.74,2.54±1.15,22.25±8.17)in normal group and(3.27±1.78,2.17±0.75,18.45±5.84)in obese groups,indicating the pain and function of the obese group were significantly improved(P<0.05).After 2 weeks and 8 weeks of treatment,the pain index of WOMAC score was consistent with the VAS score,with significant pain relie.f The functional score of WOMAC score was consistent with the Lequesne functional score,and the function was significantly improved.Conclusions ESWT can relieve the pain and function of the patients in the early stage,and the early therapeutic effect of obese patients is better than that of normal weight patients.In the course of ESWT treatment,the treatment effect of ESWT for knee osteoarthritis in obese patients was better than that in patients with normal weigh.t Obesity can affect the occurrence and development of KOA,but does not affect the treatment of KOA by ESWT.Compared with normal weight patients,obese patients are more favourable to the treatment of KOA by ESWT.关键词
肥胖/骨关节炎/膝关节/体外冲击波Key words
Obesity/Osteoarthritis/Knee/Extracorporeal shockwave therapy引用本文复制引用
刘彧,邬春虎,吴坤,邢更彦,胡晓华,张联合,陈长松,尹华东,马玉海..肥胖对体外冲击波治疗膝骨关节炎疗效的影响[J].中国医学前沿杂志（电子版）,2024,16(6):38-43,6.基金项目
浙江省医药卫生科研项目(2021432378) （2021432378）
浙江省中医药科技项目(2021ZB236) Medical Health Science and Technology Project of Zhejiang Provincial Health Commission(2021432378) （2021ZB236）
Traditional Chinese Medicine Science and Technology Project of Zhejiang(2021ZB236) （2021ZB236）
