氢吗啡酮联合布比卡因用于剖宫产术后硬膜外自控镇痛的价值OA
Value of Hydromorphone Combined with Bupivacaine on Patient-controlled Epidural Analgesia after Cesarean Section
目的:探讨氢吗啡酮联合布比卡因用于剖宫产术后硬膜外自控镇痛的价值.方法:选择2020 年 1 月—2023 年 6 月拟在新余市妇幼保健院行剖宫产术的 92 例孕妇为研究对象,按随机数表法分为观察组(n=46)和对照组(n=46).两组术后均接受硬膜外自控镇痛泵,对照组使用药物为布比卡因,观察组使用氢吗啡酮+布比卡因.比较两组术后疼痛、镇痛泵使用情况、泌乳情况、不良反应及恢复质量.结果:观察组术后 4、8、12、24、48 h视觉模拟评分法(VAS)评分均低于对照组,镇痛泵首次按压时间晚于对照组,术后 48 h内镇痛泵按压次数少于对照组,产后泌乳启动时间早于对照组,术后 48 h 40 项恢复质量评分量表(QoR-40)各项得分及总分均高于对照组,差异均有统计学意义(P<0.05);两组不良反应发生率、产后 48 h内的泌乳量充足占比比较,差异均无统计学意义(P>0.05).结论:氢吗啡酮联合布比卡因用于剖宫产术后硬膜外自控镇痛能有效缓解术后疼痛,尽早开启产后泌乳,保证良好恢复质量,且未明显增加不良反应.
Objective:To explore the value of Hydromorphone combined with Bupivacaine on patient-controlled epidural analgesia after cesarean section.Method:A total of 92 gravidas who planned to undergo cesarean section in Maternity&Child Care Center of Xinyu from January 2020 to June 2023 were selected as the study objects,and were divided into observation group(n=46)and control group(n=46)according to random number table method.Both groups received patient-controlled epidural analgesia after surgery.The control group used Bupivacaine,and the observation group used Hydromorphone+Bupivacaine.Postoperative pain,analgesia pump use,lactation,adverse reactions and recovery quality were compared between the two groups.Result:The VAS scores of the observation group were lower than those of the control group at 4,8,12,24 and 48 h after surgery,the first compression time of analgesia pump was later than that of control group,the number of analgesia pump compressions within 48 h after surgery was less than that of control group,the start time of postpartum lactation was earlier than that of control group,each item scores and total scores of 40-item quality of recovery score(QoR-40)48 h after surgery were higher than those of control group,the differences were statistically significant(P<0.05).There were no significant differences in the incidence of adverse reactions and the proportion of adequate lactation volume within 48 hours after delivery between the two groups(P>0.05).Conclusion:Hydromorphone combined with Bupivacaine on patient-controlled epidural analgesia after cesarean section can effectively relieve postoperative pain,start postpartum lactation as soon as possible,ensure good recovery quality,and do not significantly increase adverse reactions.
周盼;刘剑波;杨杰文
新余市妇幼保健院麻醉科 江西 新余 338000
氢吗啡酮布比卡因剖宫产术硬膜外自控镇痛
HydromorphoneBupivacaineCesarean sectionPatient-controlled epidural analgesia
《中国医学创新》 2024 (016)
103-106 / 4
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