中国医学前沿杂志(电子版)2024,Vol.16Issue(6):58-64,7.DOI:10.12037/YXQY.2024.06-10
微小RNAs在外周神经损伤修复中作用的研究进展
Research progress of the role of miRNAs in peripheral nerve repair
摘要
Abstract
microRNAs(miRNAs)are a class of non-coding RNAs about 22 nucleotides in length that play a vital role in neural development,regeneration and disease.After peripheral nerve injury,many miRNAs are differentially expressed,and these differentially expressed miRNAs participate in neural repair and regeneration by negatively regulating the expression of downstream target genes.In this review,the role of miRNAs in peripheral nerve regeneration will be summarized,and potential strategies will be provided for the treatment of peripheral nerve injury.关键词
周围神经损伤/微小RNA/施万细胞/DRG神经元/巨噬细胞Key words
Peripheral nerve injury/MicroRNA/Schwann cells/DRG neurons/Macrophages引用本文复制引用
王家彦,朱明媚,汤欣..微小RNAs在外周神经损伤修复中作用的研究进展[J].中国医学前沿杂志(电子版),2024,16(6):58-64,7.基金项目
The National Natural Science Foundation of China(82272167) 国家自然科学基金(82272167) (82272167)