中国医学创新2024,Vol.21Issue(16):184-188,5.DOI:10.3969/j.issn.1674-4985.2024.16.041
白细胞介素-8与类风湿关节炎关联性研究进展
Research Progress on the Relationship between Interleukin-8 and Rheumatoid Arthritis
摘要
Abstract
Rheumatoid arthritis(RA)is a polyarticular chronic inflammatory autoimmune disease,and its pathogenesis mainly includes inflammatory response,cartilage destruction and bone erosion and angiogenesis,which are closely related to inflammatory factors.Studies have shown that interleukin-8(IL-8)is an important member of inflammatory factors,so this paper reviews the mechanism of IL-8 in the occurrence and development of RA from the three aspects of inflammation,cartilage destruction and bone erosion and angiogenesis.The paper clarifies the role of interleukin-8 in the pathogenesis of RA by describing the correlation between interleukin-8 and RA,with the aim of providing a new reference basis for future in-depth research on RA.关键词
类风湿关节炎/白细胞介素-8/趋化因子/炎症/骨破坏/血管翳Key words
Rheumatoid arthritis/Interleukin-8/Chemokine/Inflammation/Bone destruction/Pannus引用本文复制引用
王振东,杨娟娟,李浩林,金芳梅,程伟刚,王海东..白细胞介素-8与类风湿关节炎关联性研究进展[J].中国医学创新,2024,21(16):184-188,5.基金项目
国自然科学基金项目(82260880) (82260880)
甘肃省名中医传承工作室建设项目(国中医药规财函[2021]242号) (国中医药规财函[2021]242号)