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白细胞介素-8与类风湿关节炎关联性研究进展

王振东 杨娟娟 李浩林 金芳梅 程伟刚 王海东

中国医学创新2024,Vol.21Issue(16):184-188,5.
中国医学创新2024,Vol.21Issue(16):184-188,5.DOI:10.3969/j.issn.1674-4985.2024.16.041

白细胞介素-8与类风湿关节炎关联性研究进展

Research Progress on the Relationship between Interleukin-8 and Rheumatoid Arthritis

王振东 1杨娟娟 1李浩林 1金芳梅 2程伟刚 1王海东2

作者信息

  • 1. 甘肃中医药大学 甘肃 兰州 730000
  • 2. 甘肃省中医院风湿骨病中心 甘肃 兰州 730050
  • 折叠

摘要

Abstract

Rheumatoid arthritis(RA)is a polyarticular chronic inflammatory autoimmune disease,and its pathogenesis mainly includes inflammatory response,cartilage destruction and bone erosion and angiogenesis,which are closely related to inflammatory factors.Studies have shown that interleukin-8(IL-8)is an important member of inflammatory factors,so this paper reviews the mechanism of IL-8 in the occurrence and development of RA from the three aspects of inflammation,cartilage destruction and bone erosion and angiogenesis.The paper clarifies the role of interleukin-8 in the pathogenesis of RA by describing the correlation between interleukin-8 and RA,with the aim of providing a new reference basis for future in-depth research on RA.

关键词

类风湿关节炎/白细胞介素-8/趋化因子/炎症/骨破坏/血管翳

Key words

Rheumatoid arthritis/Interleukin-8/Chemokine/Inflammation/Bone destruction/Pannus

引用本文复制引用

王振东,杨娟娟,李浩林,金芳梅,程伟刚,王海东..白细胞介素-8与类风湿关节炎关联性研究进展[J].中国医学创新,2024,21(16):184-188,5.

基金项目

国自然科学基金项目(82260880) (82260880)

甘肃省名中医传承工作室建设项目(国中医药规财函[2021]242号) (国中医药规财函[2021]242号)

中国医学创新

1674-4985

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