哺乳期产妇钙磷代谢及骨密度变化OA北大核心CSTPCD

Lactation is a special period of calcium and phosphorus metabolism in the body,in which a series of changes have happened in maternal bone metabolism and bone mineral density upon the function of calciotropic and phos-photropic hormones in order to provide adequate calcium to their neonate through breast milk.In this article the character-istics of calcium and phosphorus metabolism and bone mass change in lactation were reviewed.During lactation,it is re-ported that the serum calcium level remains normal,the level of serum phosphorus increases,maternal bone turnover markers increase,and women have a transient loss of bone mineral density.Above changes are related to an increasing parathyroid hormone related protein(PTHrP),prolactin(PRL)level and a decreasing estradiol(E2)level.However,the level of maternal bone metabolism and bone mineral density will gradually recover to the pre-pregnancy level after the cease of lactation and recovery of menstruation.