中华骨质疏松和骨矿盐疾病杂志2024，Vol.17Issue(3)：259-265,7.DOI:10.3969/j.issn.1674-2591.2024.03.009
哺乳期产妇钙磷代谢及骨密度变化
Changes of calcium and phosphorus metabolism and bone mineral density in lactation
摘要
Abstract
Lactation is a special period of calcium and phosphorus metabolism in the body,in which a series of changes have happened in maternal bone metabolism and bone mineral density upon the function of calciotropic and phos-photropic hormones in order to provide adequate calcium to their neonate through breast milk.In this article the character-istics of calcium and phosphorus metabolism and bone mass change in lactation were reviewed.During lactation,it is re-ported that the serum calcium level remains normal,the level of serum phosphorus increases,maternal bone turnover markers increase,and women have a transient loss of bone mineral density.Above changes are related to an increasing parathyroid hormone related protein(PTHrP),prolactin(PRL)level and a decreasing estradiol(E2)level.However,the level of maternal bone metabolism and bone mineral density will gradually recover to the pre-pregnancy level after the cease of lactation and recovery of menstruation.关键词
哺乳期/钙磷代谢/骨密度Key words
lactation/calcium and phosphorus metabolism/bone mineral density分类
医药卫生引用本文复制引用
陈莹莹,刘燕萍,王鸥..哺乳期产妇钙磷代谢及骨密度变化[J].中华骨质疏松和骨矿盐疾病杂志,2024,17(3):259-265,7.基金项目
中央高水平医院临床科研业务费资助(2022-PUMCH-B-014) （2022-PUMCH-B-014）
围孕期维生素D营养状态管理对妊娠结局改善的临床队列研究(ChiCTR 1900024080) （ChiCTR 1900024080）
