中华骨质疏松和骨矿盐疾病杂志2024，Vol.17Issue(3)：266-271,6.DOI:10.3969/j.issn.1674-2591.2024.03.010
成骨不全症儿童的骨骼表型影像测量研究进展
Advances in imaging assessment of skeletal phenotype of children with osteogenesis imperfecta
摘要
Abstract
Osteogenesis imperfecta(OI)is the most common monogenic skeletal disorders,characterized by recurrent fractures,skeletal deformities,and short stature.Accurate and quantitative evaluation of skeletal phenotype is cru-cial for judging the severity,formulating treatment plans,and predicting prognosis of OI.Currently,the most common as-sessment methods,such as X-ray radiography and dual-energy X-ray absorptiometry,can not fully capture the properties of bone micro-architecture and biomechanism.Recently,a variety of new radiographic assessment techniques,including the trabecular bone score,high-resolution peripheral quantitative CT,and magnetic resonance imaging,can quantitatively evalu-ate bone micro-architecture and biomechanical properties,and provide comprehensive information about skeletal phenotypes and bone fracture risk of children with OI,which deserve further consideration and application.关键词
成骨不全/骨小梁评分/高分辨外周骨定量计算机体层成像/磁共振成像Key words
osteogenesis imperfecta/trabecular bone score/high-resolution peripheral quantitative CT/magnetic resonance imaging分类
医药卫生引用本文复制引用
刘家怡,李梅..成骨不全症儿童的骨骼表型影像测量研究进展[J].中华骨质疏松和骨矿盐疾病杂志,2024,17(3):266-271,6.基金项目
国家重点研发计划(2021YFC2501700) （2021YFC2501700）
中央高水平医院临床科研业务费资助(2022-PUMCH-D-006,2022-PUMCH-B-014) （2022-PUMCH-D-006,2022-PUMCH-B-014）
